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Müllerian duct



Müllerian duct
Urogenital sinus of female human embryo of eight and a half to nine weeks old.
Tail end of human embryo, from eight and a half to nine weeks old.
Latin d. paramesonephricus
Gray's subject #252 1206
Carnegie stage 17
Precursor Intermediate mesoderm
MeSH Mullerian+Ducts
Dorlands/Elsevier d_29/12315002

The Müllerian ducts (or paramesonephric ducts) are paired ducts of the embryo which run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, it will develop to form the fallopian tubes, uterus, and the upper portion of the vagina. It is tissue of mesodermal origin.

Contents

Regulation of development

The development of the Müllerian ducts is controlled by the presence or absence of "AMH", or Anti-müllerian hormone (also known as "MIF" for "Müllerian inhibiting factor", or "MIH" for "Müllerian inhibiting hormone").

male embryogenesis The testes produce AMH and as a result the development of the Müllerian ducts is inhibited. Disturbances can lead to persistent müllerian duct syndrome. The ducts disappear except for the vestigial vagina masculina and the appendix testis.
female embryogenesis The absence of AMH results in the development of female reproductive organs, as noted above. Disturbance in the development may result in uterine absence (Mullerian agenesis) or uterine malformations. The ducts develop into the upper vagina, cervix, uterus and oviducts.

Eponym

They are named after Johannes Peter Müller, a physiologist who described these ducts in his text "Bildungsgeschichte der Genitalien" in 1830.

Additional images

See also

v • d • e
Prenatal development/mammalian embryogenesis - Development of the urinary and reproductive organs
General Urinary/Reproductive systemCloacal membrane - Cloaca - Urethral groove - Urogenital sinus - Urachus - Urogenital folds
Kidney developmentNephrogenic cord - Nephrotome - Pronephros - Mesonephros (Mesonephric tubules)
Ureteric bud - Metanephric blastema
Fetal genital development - primarily internalGonadal ridge - Sex cord (Cortical cords, Testis cords)
Pronephric duct/Wolffian duct/mesonephric duct - Müllerian duct/paramesonephric ducts (Vaginal plate)
Primarily externalGenital tubercle - Phallus - Labioscrotal folds
Gubernaculum - Processus vaginalis
see also list of homologues of the human reproductive system
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Müllerian_duct". A list of authors is available in Wikipedia.
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