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His work has led to several rewards  for both accuracy and, even more importantly, for great reductions in the cost to patients of having quantitative lipoprotein fractionation; it is no longer just an expensive research tool but has become low enough in cost for most physicians and patients to use the methodology to greatly improve treatment strategies and greatly reducing cardiovascular event rates without resorting to only arterial bypass surgery or angioplasty/stents to treat the symptoms of advanced disease, often after the individual has become permanently disabled.
As of early 2007, the COURAGE clinical trial  , reported during the ACC convention, which compared "optimal medical therapy" with or without additional angioplasty +/- stents, demonstrated that angioplasty +/- stents did not improve survival over "optimal medical therapy". The success of "optimizing" lipoprotein levels, not just to low adult but to at or near childhood levels, before the typical onset of atheromas, the key lesion of atherosclerosis, is one of the most effective results of "optimal medical therapy".
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Jim_Otvos". A list of authors is available in Wikipedia.|