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Howel-Evans syndrome is an extremely rare condition in which the skin of the palms of the hands, and soles of the feet, are affected (hyperkeratosis). The effects on the palms and soles is called tylosis, and in Howel-Evans syndrome, there is a predisposition to oesophageal cancer, particularly squamous cell carcinoma.
Additional recommended knowledge
Howel-Evans syndrome was described in 1996 as being identical with palmoplantar ectodermal dysplasia type III.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Howel-Evans_syndrome". A list of authors is available in Wikipedia.|