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Harrington–Hollingsworth Experiment



Title of a 1950 experiment in hematology, where the academic staff of Barnes Hospital gave themselves transfusions of the plasma from a patient with ITP to observe the effect on platelet counts in normal subjects. The staff observed reduced platelet counts that recovered after a period of several days. This experiment established the autoimmune etiology of ITP. [1] [2]

Additional recommended knowledge


  1. ^ Schwartz RS (2007). "Immune thrombocytopenic purpura--from agony to agonist". N. Engl. J. Med. 357 (22): 2299–301. doi:10.1056/NEJMe0707126. PMID 18046034.
  2. ^ HARRINGTON WJ, MINNICH V, HOLLINGSWORTH JW, MOORE CV (1951). "Demonstration of a thrombocytopenic factor in the blood of patients with thrombocytopenic purpura". J. Lab. Clin. Med. 38 (1): 1–10. PMID 14850832.
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Harrington–Hollingsworth_Experiment". A list of authors is available in Wikipedia.
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