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Gray baby syndrome
Gray baby syndrome (also termed Gray or Grey syndrome) is a rare but serious side effect that occurs in newborn infants (especially premature babies) following the intravenous administration of the antibiotic chloramphenicol.
Additional recommended knowledge
Newborn infants are predisposed to this condition because they do not yet have fully functional liver enzymes, nor do they have enough enzymes to handle the drug.
Toxic levels of chloramphenicol after 2–9 days result in:
Chloramphenicol therapy is discontinued immediately; exchange transfusion may be required to remove the drug.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Gray_baby_syndrome". A list of authors is available in Wikipedia.|