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Dorsolateral prefrontal cortex
The dorsolateral prefrontal cortex (DL-PFC or DLPFC) is the last area (45th) to develop (myelinate) in the human cerebrum. A more restricted definition of this area describes it as roughly equivalent to Brodmann's areas 9 and 46, according to a broader definition DL-PFC consists of the lateral portions of Brodmann’s areas 9 – 12, of areas 45, 46, and the superior part of area 47. These regions mainly receive their blood supply from the middle cerebral artery. With respect to neurotransmitter systems, there is evidence that dopamine plays a particularly important role in DL-PFC.
Additional recommended knowledge
DL-PFC serves as the highest cortical area responsible for motor planning, organization, and regulation. It plays an important role in the integration of sensory and mnemonic information and the regulation of intellectual function and action. It is also involved in working memory. However, DL-PFC is not exclusively responsible for the executive functions. All complex mental activity require the additional cortical and subcortical circuits that DL-PFC is connected with.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Dorsolateral_prefrontal_cortex". A list of authors is available in Wikipedia.|