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Cullen's sign is blue-black bruising of the area around the umbilicus.
Additional recommended knowledge
Thomas. S. Cullen (1869-1953) was an obstetrician and first described the sign in ruptured ectopic pregnancy in 1916.
This sign takes 24-48 hours to appear and predicts a severe attack of acute pancreatitis, with mortality rising from 8-10% to 40%.
It may be accompanied by Grey-Turner's sign (bruising of the flank).
Importance of the sign is on a decline since better diagnostic modalities are now available
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Cullen's_sign". A list of authors is available in Wikipedia.|