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Bromhexine



Bromhexine
Systematic (IUPAC) name
2,4-dibromo-6-{[cyclohexyl(methyl)amino]methyl}aniline
Identifiers
CAS number  ?
ATC code R05CB02
PubChem 2442
Chemical data
Formula C14H20Br2N2 
Mol. mass 376.13
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

Bromhexine is a mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus.

Function

Bromhexine supports the body's own natural mechanisms for clearing mucus from the respiratory tract.

It is secretolytic: that is, it increases the production of serous mucus in the respiratory tract and makes the phlegm thinner and less sticky. This contributes to a secretomotoric effect: it helps the cilia - tiny hairs that line the respiratory tract - to transport the phlegm out of the lungs. For this reasons it is often added to some antitussive (cough) syrups.

Sometimes it is replaced by its metabolite ambroxol, as in Mucosolvan or Mucoangin.

Brand names

  • Bisolvon Forte
  • Hoesttabletten Bromhexine HCl
  • Paxirasol
  • Barkacin
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Bromhexine". A list of authors is available in Wikipedia.
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