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  Antennapedia is a hox gene first discovered in Drosophila which controls the placement of legs. A loss-of-function mutation in the regulatory region of this gene can result in the development of the second leg pair into ectopic antennae. By contrast gain-of-function alleles convert antenna into ectopic legs.

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This is just one illustration of the tendency of organisms to exhibit variations on a theme, modulated repetition. Legs and antennae are related much as molars and incisors or fingers and thumbs, arms and legs are.

Antennapedia also refers to a gene complex in Drosophila which is responsible for formation and differentiation of the thoracic and head segments of the fly's body.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Antennapedia". A list of authors is available in Wikipedia.
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