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2-Aminoisobutyric acid

2-Aminoisobutyric acid
Systematic (IUPAC) name
Alpha-Aminoisobutyric acid
CAS number 62-57-7
ATC code  ?
PubChem 6119
DrugBank EXPT00471
Chemical data
Formula C4H9NO2 
Mol. mass 103.121 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.


Legal status
Routes  ?

2-Aminoisobutyric acid, or α-aminoisobutyric acid (AIB) or α-methylalanine or 2-methylalanine, is an amino acid with the structural formula is H2N-C(CH3)2-COOH.

Additional recommended knowledge

It is contained in some antibiotics of fungal origin, eg. alamethicin and some lantibiotics. It is not one of the proteinogenic amino acids and rather rare in nature.

α-Aminoisobutyric acid is a strong helix inducer in peptides. Its oligomers form 3-10 helices.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "2-Aminoisobutyric_acid". A list of authors is available in Wikipedia.
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