Embryonic Stem Cells

Our biological history can be traced back to a small group of cells called embryonic stem cells, which through cell division, give rise to cells that specialise to perform a specific role in the body - a process known as differentiation. Understanding when and how embryonic stem cells specialise pro more

How is it possible that so many different and highly specific neurons arise in the brain? A mathematic model developed by researchers from the University of Basel’s Biozentrum demonstrates that different variants of genes enable such a random diversity. The scientists describe in “Cell Reports” that more

Researchers from Drexel University College of Medicine and the University of Texas at Austin improved respiratory function in rodents with spinal cord injuries after successfully transplanting a special class of neural cells, called V2a interneurons. Their results indicate that these lab-grown cells more

Automated monitoring and data collection contribute to significant time savings when using the xCELLigence System, with only a few minutes of extra setup time. For example, in a 96-well plate, 32 different conditions can be tested in triplicate; the more

Exocrine glands have been shown to be potential sources of pluri-/multipotent adult stem cells that are highly versatile as demonstrated for pancreas, testis, salivary glands, and sweat glands. Primary cultures of these adult stem cells have the capa more

It has been 20 years since the first derivation of human embryonic stem cells. That milestone marked the start of a scientific and public fascination with stem cells, not just for their biological properties but also for their potentially transformative medical uses. The next two decades of stem cel more

Marine Drugs, Vol. 16, Pages 192: A Novel Atypical PKC-Iota Inhibitor, Echinochrome A, Enhances Cardiomyocyte Differentiation from Mouse Embryonic Stem Cells Marine Drugs doi: 10.3390/md16060192 Authors: Hyoung Kyu Kim Sung Woo Cho Hye Jin Heo Seung Hun Jeong Min Kim Kyung Soo Ko more

In mouse embryonic stem cells (mESCs), the expression of provirus and endogenous retroelements is epigenetically repressed. Although many cellular factors involved in retroelement silencing have been identified, the complete molecular mechanism remains elusive. In this study, we performed a genome- more