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Drug Resistance

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  • Bacterial lifestyle alters the evolution of antibiotic resistance

    How bacteria live -- whether as independent cells or in a communal biofilm -- determines how they evolve antibiotic resistance, which could lead to more personalized approaches to antimicrobial therapy and infection control. University of Pittsburgh School of Medicine researchers repeatedly exposed more

  • Multidrug-resistant malaria spreading in Asia

    Genomic surveillance has revealed that malaria resistance to two first-line antimalarial drugs has spread rapidly from Cambodia to neighbouring countries in Southeast Asia. Researchers from the Wellcome Sanger Institute, University of Oxford and Mahidol University, Bangkok, discovered that descendan more

  • Drug resistance: Preventing drugs from being transported

    Certain membrane proteins specialise in transporting molecules out of cells – a problem for the efficacy of cancer medication and antibiotics. An international research team has investigated the transport mechanism of a bacterial membrane protein using an artificially produced antibody fragment. The more

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Definition

Drug resistance

Drug resistance Drug resistance is the reduction in effectiveness of a drug in curing a disease or improving a patient's symptoms. When the drug is not intended to kill or inhibit a pathogen , then the term is equivalent to dosage failure or ... more

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