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DNA Damage

News DNA Damage

  • DNA repair: Opening the hatch to heal the break

    LMU researchers have determined the structure of a key enzyme complex that is involved in DNA repair, and traced the cycle of conformational changes that it undergoes while performing its biochemical function. Various types of DNA damage can have serious repercussions, both for the individual cells more

  • Stem cells moonlight to protect the stomach from bacterial invaders

    Our mucosal surfaces are constantly exposed to numerous bacterial species, some of which can induce DNA damage in host cells. Normally this remains inconsequential, as the rapid turnover of the mucosa means damaged cells are shed within days. However, if the long-lived stem cells that continually gi more

  • A new mechanism for accessing damaged DNA

    UV light damages the DNA of skin cells, which can lead to skin cancer. But this process is counteracted by the DNA repair machinery, acting as a molecular sunscreen. It has been unclear, however, how repair proteins work on DNA tightly packed in chromatin, where access to DNA damage is restricted by more

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Videos DNA Damage

ICR Researchers use Cryo-Electron Microscopy to zoom in on DNA code being read in cells

ICR Researchers led by Dr Alessandro Vannini have captured images of molecular machinery called RNA Polymerase III in the act of transcribing a gene in exquisite and unprecedented detail. Animation provided by Phospho Biomedical Animation more

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