Cube Biotech GmbH

The Strep-tag technology offers a versatile system for purifying and analyzing proteins. It enables exceptional protein purity (>95%) through highly specific binding properties, while preserving the activity of the target protein. Thanks to the mild elution conditions, the natural protein structure is maintained, making it ideal for protein interaction studies. The high-affinity variant, Strep-TactinXT, facilitates efficient protein purification regardless of protein class or size, even with challenging proteins or low abundant proteins. It offers stability over a wide pH range and is reusable, which significantly reduces costs. Magnetic MagStrep beads, coupled with Strep-TactinXT, enable rapid purification and complex pull-down assays. Additionally, Strep-TactinXT 4Flow agarose reagents provide effective purification even from diluted samples. In analytical applications, picomolar affinity supports assays such as SPR, BLI, high-throughput screening, and diagnostic tests. Microtiter plates coated with Strep-TactinXT enable antibody-free protein immobilization, ensuring reproducible results. The technology encompasses the entire workflow, from cloning and purification to analyzes such as ELISA, FACS, SPR, and Western blot.