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The submerged cultivation of human, animal and plant cells for research or production purposes is still a fine art: most cell cultures are sensitive to mechanical forces and require special nutrients and O2/CO2 concentrations. Due to the low cell division rates, the risk of contamination is always an issue. Special microtiter plates, bioreactors and sensors are only a few of the special cell culture products available.
HAMILTON Robotics designs and manufactures fully automated robotic systems. The products range from unique, custom laboratory automation solutions (Turnkey Solutions) on standard applications validated through partnership programs with renowned biotechnology companies as well as OEM solutions to the more
The Sartorius Group is a leading international laboratory and process technology provider covering the segments of biotechnology and mechatronics. Founded in 1870, the Goettingen-based company currently employs more than 4,500 persons. The major areas of activity in its biotechnology segment focu more
Takara Bio Europe and Clontech Laboratories are members of the Takara Bio Group, a leading supplier of tools for life scientists worldwide. Through our brand names Takara® and Clontech® we develop innovative technologies in the fields of Cell Biology, Molecular Biology and Proteomics. Takara Bio h more
Researchers have developed a three-dimensional 'organ on a chip' which enables real-time continuous monitoring of cells, and could be used to develop new treatments for disease while reducing the number of animals used in research. The device, which incorporates cells inside a 3D transistor made fro more
Mitochondrial disease is now thought to be the second most commonly diagnosed genetic disease worldwide, and, unfortunately, there are still no proven treatment strategies for those diagnosed. Scientists from the Max Planck Institute for Biology of Ageing in Cologne were involved in collaborations t more
Differences in production methods for therapeutic antibodies can lead to variations in their structure, depending on the recombinant procedure selected. The distinctions, which are based on a number of glycosylations, even impact antibodies’ stability. This was the result of a high-precision compari more
Cell transfection is a method of gene delivery that introduces foreign DNA into a cell. It is one of the most important approaches in modern genetic and proteomic research. With intriguing properties, transfection of primary cells is required for tis more
Transfection is the delivery of DNA, RNA, proteins, and macromelecules into eukaryotic cells. The goals for transfection include the study of gene function and regulation as well as protein expression and function. It is also used for gene silencing more
Automated monitoring and data collection contribute to significant time savings when using the xCELLigence System, with only a few minutes of extra setup time. For example, in a 96-well plate, 32 different conditions can be tested in triplicate; the more
Eukaryotic cell cultures respond to the smallest of influences. Apart from the risk of contamination, minimal changes in cultivation parameters can affect the viability, growth and metabolism of the cells. In this educational webinar we will discuss Mycoplasma test methods, the effects of passage nu
Viruses, Vol. 10, Pages 302: Preclinical Testing of an Oncolytic Parvovirus in Ewing Sarcoma: Protoparvovirus H-1 Induces Apoptosis and Lytic Infection In Vitro but Fails to Improve Survival In Vivo Viruses doi: 10.3390/v10060302 Authors: Jeannine Lacroix Zoltán Kis Rafael Josupeit Fr more
This protocol describes viability measurements for cell cultures in a 96-well tissue culture plate using alamarBlue (resazurin). The assay can be modified to accommodate larger plates; however, for a preliminary analysis of transfection reagents and parameters of the transfection protocol on cell v more
Parkinson's disease (PD) is a progressive neurodegenerative disease characterized by the loss of dopaminergic neurons in the substantia nigra (SN) and the reduction of dopamine levels in the striatum. Although details of the molecular mechanisms underlying dopaminergic neuronal death in PD remain un more
GBI Research, the leading business intelligence provider has released its latest research report, “Biopharmaceutical Manufacturing in India, China and South Korea - Regulatory Framework, Infrastructure Support and Discovery Funding Create an Environment Conducive to Growth”. The report provides an a more
GBI Research's report, “Upstream Processing in Biopharmaceuticals - Increasing Use of Low-Cost Disposable Bioreactors to Drive the Upstream Bioprocessing Market”, provides the key to market data on overall upstream process, Contract Manufacturing Organization (CMO) market for upstream processing, an more
Introduction The global blood plasma-derived products market has shown consistent growth over the period 2002-2009 and the rapid increase in cases of Hemophilia, low treatment cost to patients and rising ageing population are the major factors that will be driving the market for plasma-derived produ more
European Collection of Cell Cultures The European Collection of Cell Cultures houses and supplies cell line s. It is a commercial venture of the Health Protection Agency . The collection is held in Porton Down . External links *Official home page more
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