Plaques

News Plaques

• Innovative medication to shatter blood clots with light

  Earthquakes, snakes, forest fires – none rob humans of life more frequently than the tiny clumps of fat, calcium and cholesterol we know as blood clots. Every fifth human dies when a blood clot, or more correctly cholesterol plaque, loosens and gets stuck somewhere in the heart or brain causing hear more

• Suppressing protein may stem Alzheimer's disease process

  Scientists funded by the National Institutes of Health have discovered a potential strategy for developing treatments to stem the disease process in Alzheimer's disease. It's based on unclogging removal of toxic debris that accumulates in patients' brains, by blocking activity of a little-known regu more

• New light shed on early stage Alzheimer's disease
  

  The disrupted metabolism of sugar, fat and calcium is part of the process that causes the death of neurons in Alzheimer's disease. Researchers from Karolinska Institutet have now shown, for the first time, how important parts of the nerve cell that are involved in the cell's energy metabolism operat more

White papers Plaques

• Real-time and Dynamic Monitoring of Virus-mediated Cytopathogenicity
  

  To understand overall infectivity, virus progression and disease onset it is important to perform a detailed examination of cytopathic effects. Depending on the type of viruses and cells, different cytopathic effects might be observed dependent on the timepoint of infection (e.g., during the growth or stationary phase) and the amount of virus used. One of the most common methods for measuring lysogenic/lytic activity of viruses is the plaque test [1]. In this assay culture plates with confluent cells that are sensitive towards the specific virus type/strain are used. Lytic activity of a virus is detected by macroscopic analysis of plaques in a confluent cell layer after staining (e.g., with crystal violet). This technique is an end-point assay and it is well-suited to determine viral titers; however, it provides no information about the onset of cytopathic effects and kinetics of the viral replication. Moreover, infection with a number of viruses (e.g., attenuated mutants) leads to the formation of small and more

• Miniaturised Platelet Aggregation Assays using the NOVOstar Microplate Reader
  

  Platelet aggregation is a “gold standard” assay of platelet function in the research and clinical laboratory settings which is conventionally measured with aggregometers requiring large volumes of platelet suspensions and only in low throughput format. With the NOVOstar microplate reader from BMG LABTECH we present an alternative optical method to measure platelet aggregation using small volumes in 96-well format more

Publications Plaques

• Inhibition of galectin-3 reduces atherosclerosis in apolipoprotein E-deficient mice

  Atherosclerosis is a major risk factor for cardiovascular disease (CVD) and stroke. Galectin-3 is a carbohydrate-binding lectin implicated in the pathophysiology of CVD and is highly expressed within atherosclerotic lesions in mice and humans. The object of this present study was to use genetic del more

• Proteomics of plaques and novel sources of potential biomarkers for atherosclerosis

  Cardiovascular disease (CVD) is the leading cause of death and loss of productive life years in the world. The underlying syndrome of CVD, atherosclerosis, is a complex disease process which involves lipid metabolism, inflammation, innate and adaptive immunity, and many other pathophysiological as more

• Comparison of grey scale median (GSM) measurement in ultrasound images of human carotid plaques using two different softwares

  Summary Grey scale median (GSM) measured on ultrasound images of carotid plaques has been used for several years now in research to find the vulnerable plaque. Centres have used different software and also different methods for GSM measurement. This has resulted in a wide range of GSM values and more

Market studies Plaques

• Eckert & Ziegler Strahlen- und Medizintechnik AG (EUZ) - Financial and Strategic SWOT Analysis Review

  Eckert & Ziegler Strahlen- und Medizintechnik AG (Eckert & Ziegler) is engaged in the development, manufacture and marketing of isotope technology components, radiation equipment, radio-pharmaceuticals, medical technology equipment and other related products. The company develops medical nuclear im more

• International Brachytherapy S.A. (IBT) - Financial and Strategic SWOT Analysis Review

  International Brachytherapy S.A. (IBT Bebig) is a Europe-based medical device company, focusing on cancer treatment by radiation technology. The company is engaged in the design, development and distribution of interstitial implants used in brachytherapy for the treatment of cancer. It focuses on ca more

• International Brachytherapy S.A. (EZBG) - Financial and Strategic SWOT Analysis Review

  International Brachytherapy S.A. (IBT Bebig) is a Europe-based medical device company, focusing on cancer treatment by radiation technology. The company is engaged in the design, development and distribution of interstitial implants used in brachytherapy for the treatment of cancer. It focuses on ca more

Websites Plaques