Drug Discovery

Companies Drug Discovery

Hamilton Robotics GmbH, Germany

HAMILTON Robotics designs and manufactures fully automated robotic systems. The products range from unique, custom laboratory automation solutions (Turnkey Solutions) on standard applications validated through partnership programs with renowned biotechnology companies as well as OEM solutions to the more

MP Biomedicals S.A.S., France

MP Biomedicals is a global corporation, with headquarters in Santa Ana, California, USA and regional offices in Europe, Asia Pacific and Australia. The corporation manufactures and sells more than 55,000 ISO, FDA and CE certified products and is represented on all continents: NA, LATAM, APAC and EME more

CCS Cell Culture Service GmbH, Germany

CCS generates stably transfected cell lines for cell based drug screening and produces recombinant proteins from mammalian and insect cells. more

Products Drug Discovery

The top class multi-mode reader for assay development

No compromise – Tecan’s Infinite® M 1000 PRO is the top class multi-mode reader for assay development - speed, high flexibility, outstanding results more

Sterile plates enhance cellular growth applications

BactiGrowth plates from Porvair Sciences Ltd. offer a contamination free deep-well microplate optimised for high yield growth of bacteria, yeast and more

News Drug Discovery

• Plate reader for drug discovery
  

  The trend towards automated high content assays, particularly for systems biology and drug discovery, has stimulated the development of automated fluorescence microscopy systems to image sample arrays. Today’s commercially available high content analysis (HCA) instruments predominantly employ fluore more

• Lead Discovery Center participates in new pan-European drug discovery platform

  The European Lead Factory, a novel platform for innovative drug discovery, was launched early February by an international consortium of 30 partners including the Lead Discovery Center GmbH (LDC). LDC is an expert in the discovery and generation of small molecule lead series by translating basic res more

• Learning from the linker

  Mature cells can be reprogrammed to pluripotency and thus regain the ability to divide and differentiate into specialized cell types. Although these so-called induced pluripotent stem cells (iPS cells) represent a milestone in stem cell research, many of the biochemical processes that underlie repro more

White papers Drug Discovery

• Non-Invasive Real-Time Cell Analytics for Drug Discovery
  

  Roche’s xCELLigence Cardio Instrument is a medium-throughput cell analyzer using impedance recording to monitor cardiac beating and cellular events in real time. The instrument features high resolution detection rate and frequency measurement technology driven by dedicated software. Unlike patch clamp recordings, this system monitors cardiac cell responsivity continuously in both short-term and more

Publications Drug Discovery

• A Novel Manganese Complex, Mn-(II) N-(2-Hydroxy Acetophenone) Glycinate overcomes Multidrug-Resistance in Cancer

  Publication date: Available online 9 May 2013 Source:European Journal of Pharmaceutical Sciences Author(s): Ruma Dey Ghosh , Kaushik Banerjee , Satyajit Das , Avishek Ganguly , Paramita Chakraborty , Avijit Sarkar , Mitali Chatterjee , Soumitra K Choudhuri Multidrug resistance (MDR) re more

• Towards an efficient approach to identify molecular scaffolds possessing selective or promiscuous compounds

  Abstract The concept of a recurrent scaffold present in a series of structures is common in medicinal drug discovery. We present a scaffold analysis of compounds screened across 100 sequence‐unrelated proteins to identify scaffolds that drive promiscuity or selectivity. Selectivity and promiscui more

• Pharmacogenetics in clinical practice: how far have we come and where are we going?

  Recent years have seen great advances in our understanding of genetic contributors to drug response. Drug discovery and development around targeted genetic (somatic) mutations has led to a number of new drugs with genetic indications, particularly for the treatment of cancers. Our knowledge of genet more

Market studies Drug Discovery

• Chemizon, Inc. - Strategic SWOT Analysis Review

  Chemizon, Inc. (Chemizon) is a biotechnology company, engaged in the discovery and development of innovative therapeutics. The company owns an integrated drug discovery platform based on medical chemistry, biology, computational chemistry, ADME/DMPK and pharmacology to accelerate drug development pr more

• Protein and Peptide-based Therapeutics - Trends in Drug Discovery and Development

  GBI Research, leading business intelligence provider, has released its latest research report, entitled “Protein and Peptide-based Therapeutics - Trends in Drug Discovery and Development". Over the last decade, protein and peptide-based therapeutics have attracted more and more attention in the phar more

• Epigenetics R&D Pipeline - Histone Deacetylases (HDACs) Offer the Most Promising Targets and Outnumber Other Classes of Epigenetic Targets

  GBI Research, a leading business intelligence provider, has released its latest research, entitled “Epigenetics R&D Pipeline - Histone Deacetylases (HDACs) Offer the Most Promising Targets and Outnumber Other Classes of Epigenetic Targets”. The report is built using data and information sourced from more

Websites Drug Discovery