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Clinical Trials

Companies Clinical Trials

GKM Gesellschaft für Therapieforschung mbH, Germany

GKM (Gesellschaft für Therapieforschung mbH) is an independent, family-owned contract research organization (CRO). GKM provides a comprehensive portfolio of CRO services for the pharmaceutical industry, manufacturers of medical devices and academia. Founded in 1981, GKM is headquartered in Munich, more

News Clinical Trials

  • Precision medicine breakthrough for Chronic Myeloid Leukaemia

    Scientists at the University of Glasgow have made a second significant breakthrough in the treatment of chronic myeloid leukaemia – using precision medicine to kill more than 90% of chronic myeloid leukaemia (CML) stem cells. The results are published today in the high impact journal Cancer Discover more

  • Antibody reduces harmful brain amyloid plaques in Alzheimer's patients

    Aducanumab, an antibody developed by the University of Zurich, has been shown to trigger a meaningful reduction of harmful beta-amyloid plaques in patients with early-stage Alzheimer's disease. These protein deposits in the brain are a classic sign of Alzheimer's disease and contribute to the progre more

  • Remote-controlled implantable device delivers HIV prevention drug

    A Houston Methodist research team received a nearly $4 million grant to test a transcutaneously refillable implant that administers pre-exposure prophylaxis drugs to subjects at risk of HIV-exposure. The National Institute of Allergy and Infectious Diseases (NIAID) awarded Alessandro Grattoni, Ph.D. more

All news on clinical trials

White papers Clinical Trials

  • Wyeth 'learns and confirms' in India

    Aparna Singh (AS), Program Manager with Frost & Sullivan's Chemical Materials and Foods team caught up with Dr. Michael Kolb (Dr. MK) at Frost & Sullivan's Opportunities in Lifescience Molecules: Global Partnership Summit 2006. This annual summit was more

  • Interference and HAMA problems

    Immunoassays are bioanalytical methods based on antibodies. These include ELISA, EIA, RIA, Western blotting, protein arrays, lateral flow assays, more

  • Nobel Prize for Solving the End-Replication Problem

    The Nobel Assembly awarded this year's Nobel Prize in Medicine to Elizabeth H. Blackburn, Jack W. Szostak, and Carol W. Greider for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase. With their ingenious genetic re more

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Infographics Clinical Trials

Understanding the Drug Discovery Process

As a consumer, it’s easy to be oblivious to the amount of time, work, and money that goes into the development of a drug. The cost of developing a drug that goes on to gain marketing approval was estimated to be $2,558 million in 2014, and the process can commonly last longer than a decade. Addition more

A Rough Guide to Types of Scientific Evidence

Today’s graphic looks at science in general, rather than just chemistry. It’s in a similar vein to the Rough Guide to Spotting Bad Science posted last year, but this time looking at the hierarchy of different types of scientific evidence. You might think science is science, but some evidence is rank more

Events Clinical Trials

Course
06-10-2016
Reading, GB

Good Clinical Practice and Clinical Trials Introduction

This course provides an introduction to the clinical trials process and the requirements of Good Clinical Practice (GCP).

Webinar
On-Demand

A Systematic Patient‐Derived Xenograft Based Solution for Preclinical Biomarker Discovery

Tumor heterogeneity is a major hurdle for cancer treatment success. To effectively enroll patients in clinical trials, the identification of predictive biomarkers at the preclinical stage is crucial. The use of patient-derived xenograft (PDX) tumor models facilitates the identification of biomarkers

Publications Clinical Trials

  • Natural Product-Derived Spirooxindole Fragments Serve as Privileged Substructures for Discovery of New Anticancer Agents

    Abstract: The utility of natural products for identifying anticancer agents has been highly pursued in the last decades and over 100 drug molecules in clinic are natural products or natural product-derived compounds. Natural products are believed to be able to cover unexplored chemical space that more

  • Inhibitors of Cancer Stem Cells

    Abstract: The cancer stem cell (CSC) theory is current strategy of cancer treatment. Cancers follow pathways of cancer stem cell such as Notch, Wnt and Hedgehog can be addressed with natural products or synthetic drugs to diminish the chance of new tumours. The cancer growth can also be suppressed more

  • Gene therapy for metachromatic leukodystrophy

    Leukodystrophies (LDs) are rare, often devastating genetic disorders with neurologic symptoms. There are currently no disease‐specific therapeutic approaches for these diseases. In this review we use metachromatic leukodystrophy as an example to outline in the brief the therapeutic approaches to M more

All publications on clinical trials

Market studies Clinical Trials

  • Psoriasis Global Clinical Trials Review, H1, 2012

    Introduction GlobalData's clinical trial report, “Psoriasis Global Clinical Trials Review, H1, 2012" provides data on the Psoriasis clinical trial scenario. This report provides elemental information and data relating to the clinical trials on Psoriasis. It includes an overview of the trial number more

  • Male Hypogonadism Global Clinical Trials Review, H1, 2012

    Introduction GlobalData's clinical trial report, “Male Hypogonadism Global Clinical Trials Review, H1, 2012" provides data on the Male Hypogonadism clinical trial scenario. This report provides elemental information and data relating to the clinical trials on Male Hypogonadism. It includes an overv more

  • Anal Fissure Global Clinical Trials Review, H1, 2012

    Introduction GlobalData's clinical trial report, “Anal Fissure Global Clinical Trials Review, H1, 2012" provides data on the Anal Fissure clinical trial scenario. This report provides elemental information and data relating to the clinical trials on Anal Fissure. It includes an overview of the tri more

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Definition

AIDS Clinical Trials Group

AIDS Clinical Trials Group The AIDS Clinical Trials Group (ACTG) is the largest HIV clinical trials organization in the world, playing a major role in setting standards of care for HIV infection and opportunistic diseases related to HIV and AID ... more

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