Clinical Trials

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News Clinical Trials

• EU offensive against multi-resistant bacteria
  

  Bacteria resistant to multiple antibiotics are one of the biggest health hazards of our time. In order to push the development of new antibiotic drugs fighting antimicrobial resistance (AMR), the research project TRANSLOCATION has been set up as part of the Euroepan public-private partnership Innova more

• New hope in fight against multi-resistant germs

  An increasing number of bacteria is evolving antibiotic resistance. Much-feared representatives of this steadily growing group include Staphylococci strains. At this point, multi-resistant forms of the bacterium Staphylococcus aureus - the "hospital germ" known commonly by its acronym, MRSA - can on more

• PolyPid announces positive preliminary results of clinical trial with BonyPid

  PolyPid Ltd. announced positive preliminary results of a first-in-man clinical trial with its BonyPid™ product. BonyPid™ is a combined drug and medical device product integrating bone filler and a substantial antibiotic release platform. The bone filler is resorbed and replaced by the bone during he more

White papers Clinical Trials

• Clinical Biomarkers: Novel Tools for Pharmacodynamic Applications
  

  Biomarkers are currently changing the way we diagnose and treat diseases. Today pharmacodynamic biomarkers are widely used in the industry elaborating optimal dosing of new drugs and predictive biomarkers have an enormous potential for companion diagnostics more

• Outsourcing in Pharmaceutical Industry

  Pharmaceutical industry is constantly undergoing a change. In the past pharmaceuticals had a different strategy, companies use to build all the products internally and confine access to information or resources to third parties. The past situation is changing; in-house resources are getting exhausted with a very thin product pipeline and in addition many drugs are going off patent by 2008 hampering company sales and competitiveness. It takes $800 million and 20 years for... more

• Nobel Prize for Solving the End-Replication Problem
  

  The Nobel Assembly awarded this year's Nobel Prize in Medicine to Elizabeth H. Blackburn, Jack W. Szostak, and Carol W. Greider for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase. With their ingenious genetic research and meticulous biochemical studies, they not only solved a fundamental problem in biology but also opened a new field of research and initiated the development of potential therapies against disease more

Publications Clinical Trials

• Treatment outcome of advanced pancreatic cancer patients who are ineligible for a clinical trial

  Ueda A, Hosokawa A, Ogawa K, Yoshita H, Ando T, Kajiura S, Fujinami H, Kawai K, Nishikawa J, Tajiri K, Minemura M, Sugiyama T more

• Rational development of solid dispersions via hot‐melt extrusion using screening, material characterization, and numeric simulation tools

  Abstract Effective and predictive small‐scale selection tools are inevitable during the development of a solubility enhanced drug product. For hot‐melt extrusion, this selection process can start with a microscale performance evaluation on a hot‐stage microscope (HSM). A batch size of 400 mg can more

• Fixed-dose combination of phentermine–topiramate for the treatment of obesity

  The aim of this article is to focus on the fixed-dose combination of phentermine and topiramate, a new antiobesity drug recently approved by the US FDA. The mechanisms of weight loss for each drug in monotherapy is described, followed by the rationale for its use as a combination therapy and a compr more

Market studies Clinical Trials

• Psoriasis Global Clinical Trials Review, H1, 2012

  Introduction GlobalData's clinical trial report, “Psoriasis Global Clinical Trials Review, H1, 2012" provides data on the Psoriasis clinical trial scenario. This report provides elemental information and data relating to the clinical trials on Psoriasis. It includes an overview of the trial number more

• Male Hypogonadism Global Clinical Trials Review, H1, 2012

  Introduction GlobalData's clinical trial report, “Male Hypogonadism Global Clinical Trials Review, H1, 2012" provides data on the Male Hypogonadism clinical trial scenario. This report provides elemental information and data relating to the clinical trials on Male Hypogonadism. It includes an overv more

• Anal Fissure Global Clinical Trials Review, H1, 2012

  Introduction GlobalData's clinical trial report, “Anal Fissure Global Clinical Trials Review, H1, 2012" provides data on the Anal Fissure clinical trial scenario. This report provides elemental information and data relating to the clinical trials on Anal Fissure. It includes an overview of the tri more

Websites Clinical Trials