Cancer Genes

News Cancer Genes

• Breast cancer risk gene discovery fast tracked by new technology

  An international team of researchers led by the University of Melbourne has used new technology to fast track the discovery of a breast cancer risk gene and could assist in the discovery of other cancer genes.Professor Melissa Southey of the Genetic Epidemiology Laboratory, Department of Pathology a more

• Researchers shine light on how some melanoma tumors evade drug treatment

  Researchers shine light on how some melanoma tumors evade drug treatment Findings pinpoint a critical gene involved in melanoma growth, provide a framework for discovering ways to tackle cancer drug resistance The past year has brought to light both the promise and the frustration of developing new more

• MIT biologists find that restoring the gene for cancer protein p53 slows spread of advanced tumors

  In a new study published in Nature, MIT cancer biologists show that restoring the protein p53's function in mice with lung cancer has no effect early in tumor development, but restoring the function later on could prevent more advanced tumors from spreading throughout the body. Cancer researchers more

Publications Cancer Genes

• Integration of Cancer Gene Co-expression Network and Metabolic Network To Uncover Potential Cancer Drug Targets

  Cell metabolism is critical for cancer cell transformation and progression. In this study, we have developed a novel method, named Met-express, that integrates a cancer gene co-expression network with the metabolic network to predict key enzyme-coding genes and metabolites in cancer cell metabolism. more

• Differential mutation profiles and similar intronic TP53 polymorphisms in asbestos-related lung cancer and pleural mesothelioma

  Given the interest in defining biomarkers of asbestos exposure and to provide insights into asbestos-related and cell-specific mechanisms of neoplasia, the identification of gene alterations in asbestos-related cancers can help to a better understanding of exposure risk. To understand the aetiology more

• Breakpoint Analysis of Transcriptional and Genomic Profiles Uncovers Novel Gene Fusions Spanning Multiple Human Cancer Types

  by Craig P. Giacomini, Steven Sun, Sushama Varma, A. Hunter Shain, Marilyn M. Giacomini, Jay Balagtas, Robert T. Sweeney, Everett Lai, Catherine A. Del Vecchio, Andrew D. Forster, Nicole Clarke, Kelli D. Montgomery, Shirley Zhu, Albert J. Wong, Matt van de Rijn, Robert B. West, Jonathan R. Pollack more

Websites Cancer Genes