Bioavailability

News Bioavailability

• BASF and Catalent join forces to solve bioavailability challenges

  Catalent Pharma Solutions and BASF have entered into a broad collaboration and Open Alliance to provide solutions to overcome bioavailability challenges of new molecular entities with solubility or permeability challenges. The companies aim to combine their expertise to provide pharmaceutical custom more

• Quotient Clinical and Bend Research Announce Collaboration To Accelerate Advancement of New Medicines

  Bend Research Inc. and Quotient Clinical, a business unit of Quotient Bioresearch, announced a nonexclusive collaboration that can speed the advance of compounds to clinical trials and expand options for drug delivery. The collaboration combines Bend Research’s advanced drug formulation capabiliti more

• Hybrigenics develops new oral formulations of inecalcitol

  Hybrigenics announced the filing of a patent application covering new soft gelatin capsules, tablets or drinking solutions optimized for the delivery of high doses of inecalcitol. This pharmaceutical optimization followed the demonstration of safety and the presumption of efficacy of oral doses as h more

White papers Bioavailability

• Frost & Sullivan's Global PharmAlliance 2005: Becoming the Partner of Choice
  

  Looking at the increasing trend towards partnerships and alliances in the pharmaceutical industry, Frost & Sullivan a global growth consulting company had organized a premium conference, "Global PharmAlliance 2005 - Becoming the partner of choice" in Mumbai (India). The two day event focused on giving an insight into the world of partnerships and alliances through... more

• Characterization of micelles and liposomes using the Eclipse AF4 separation system coupled to a DAWN HELEOS II MALS detector
  

  Micelles and liposomes can serve as vehicles used to solubilize and carry bioactive compounds to their site of action, thus increasing their bioavailability. First experience has been made using vitamins and enzymes as functional food additives. Moreover, micelles could be useful to deliver drugs to a defined site of action, thus reducing frequently occurring side effects of systemic drug administration. Micelles are true nano-materials with a size range of 10 to 30 nm in diameter. Ideally, they should have a narrow size distribution. Furthermore, they have to be stable and should release their active compound only in the target region. Characterization of the micelle suspensions is vital to guarantee these properties and has to cover several aspects. One important point is size distribution, which has to be determined with high resolution more

Publications Bioavailability

• pH-sensitive micelles self-assembled from multiarm star triblock copolymers 4/6AS-PCL-b-PDEAEMA-b-PPEGMA for controlled anticancer drug delivery

  Publication date: Available online 10 May 2013 Source:Acta Biomaterialia Author(s): You Qiang Yang , Bin Zhao , Zhen Dong Li , Wen Jing Lin , Can Yang Zhang , Xin Dong Guo , Ju Fang Wang , Li Juan Zhang A series of amphiphilic 4- and 6-armed star triblock copolymers poly(ε-caprolactone more

• Increased mucociliary differentiation and aquaporins formation of respiratory epithelial cells on retinoic acid-loaded hyaluronan-derivative membranes

  Publication date: June 2013 Source:Acta Biomaterialia, Volume 9, Issue 6 Author(s): Tsung-Wei Huang , Yen-Hui Chan , Huang-Wei Su , Ya-Shuan Chou , Tai-Horng Young While playing a major role in maintaining the mucociliary phenotype of respiratory epithelial cells (RECs), retinoids are cri more

• Studies on pharmacokinetic mechanism of phenytoin resistance in refractory epilepsy

  Abstract P‐glycoprotein (P‐gp) is a drug efflux pump in many organs, including the intestine and liver. Two single nucleotide polymorphisms (SNPs) of P‐gp gene, 2677G>T and 3435C>T, were reported to influence function and expression of P‐gp and have the controversial effects on drug disposition. more

Market studies Bioavailability

• Argentina Pharmaceuticals and Healthcare Report Q2 2012

  BMI View: Measured in local currency and in US dollars, the value of Argentina’s pharmaceutical market is expected to grow at double-digit rates over the five years to 2016, in large part due to inflationary pressure, even though the demand continues to grow. Risks to foreign players will remain ele more

• Oral Drug Delivery Market to 2017 - Out-licensing Proprietary Technologies for Proteins, Peptides and Small Molecules to Drive Revenue Growth

  GBI Research, the leading business intelligence provider, has released its latest research “Oral Drug Delivery Market to 2017 - Out-licensing Proprietary Technologies for Proteins, Peptides and Small Molecules to Drive Revenue Growth”. The report focuses on the current scenario of orally administere more

• Merrion Pharmaceuticals Plc (3MP) - Financial and Strategic SWOT Analysis Review

  Merrion Pharmaceuticals Plc (Merrion) is a specialty pharmaceutical company engaged in developing oral dosage forms of drugs that have poor absorption. The company’s proprietary and patented GIPET technology focuses on improving the bioavailability of drugs with poor absorption, by improving absorpt more

Websites Bioavailability