Antibodies can improve the rehabilitation of people with acute spinal cord injury

20-Dec-2024 - Antibody that Neutralizes Inhibitory Factors Involved in Nerve Regeneration Leads to Enhanced Motor Function after Acute Spinal Cord Injury. Researchers at 13 clinics in Germany, Switzerland, the Czech Republic and Spain have investigated this with promising results. For the first time, it was ...

Deciphering the secrets of spinal cord regeneration protein by protein

"With this understanding, we hope to develop new therapeutic approaches for spinal cord injury in humans in the future"

14-Nov-2023 - Scientists have long sought to understand how certain animals, such as zebrafish, are able to regrow nerve fibers and regain lost motor function after spinal cord injury. In humans, these injuries are irreparable and result in permanent loss of function, such as paralysis. An international team ...

Brain-computer interface enables thought-controlled walking after spinal cord injury

29-May-2023 - ONWARD Medical N.V, a medical device company that develops therapies to restore movement, function and independence in people with spinal cord injury (SCI), announced a paper in Nature showing that using a wireless brain-computer interface (BCI), thoughts can be used to control ARC therapy. The ...

Advancing stem cell therapy with biodegradable scaffold

New technology is aimed at central nervous system diseases and injuries

06-Nov-2018 - Rutgers scientists have created a tiny, biodegradable scaffold to transplant stem cells and deliver drugs, which may help treat Alzheimer's and Parkinson's diseases, aging brain degeneration, spinal cord injuries and traumatic brain injuries. Stem cell transplantation, which shows promise as a ...

Lab-grown neurons improve breathing in mice after spinal cord injury

08-Jun-2018 - Researchers from Drexel University College of Medicine and the University of Texas at Austin improved respiratory function in rodents with spinal cord injuries after successfully transplanting a special class of neural cells, called V2a interneurons. Their results indicate that these lab-grown ...

Human neural stem cell grafts used to repair spinal cord injuries in monkeys

28-Feb-2018 - Led by researchers at University of California San Diego School of Medicine, a diverse team of neuroscientists and surgeons successfully grafted human neural progenitor cells into rhesus monkeys with spinal cord injuries. The grafts not only survived, but grew hundreds of thousands of human axons ...

Zebrafish study reveals clues to healing spinal cord injuries

26-Jul-2017 - Fresh insights into how zebrafish repair their nerve connections could hold clues to new therapies for people with spinal cord injuries. Researchers have pinpointed key molecules that prompt damaged nerve fibres in the fish to regenerate themselves. The findings could pave the way for treatments ...

Big improvement to brain-computer interface

21-Feb-2017 - When people suffer spinal cord injuries and lose mobility in their limbs, it's a neural signal processing problem. The brain can still send clear electrical impulses and the limbs can still receive them, but the signal gets lost in the damaged spinal cord. The Center for Sensorimotor Neural ...

New pain mechanisms revealed for neurotoxin in spinal cord injury

25-Nov-2015 - A toxin released by the body in response to spinal cord injuries increases pain by causing a proliferation of channels containing pain sensors, new research shows, and this hypersensitivity also extends to peripheral nerves in the limbs far from the injury site. Findings could point to a new ...

Completely paralyzed man voluntarily moves his legs

02-Sep-2015 - A 39-year-old man who had had been completely paralyzed for four years was able to voluntarily control his leg muscles and take thousands of steps in a "robotic exoskeleton" device during five days of training a team of UCLA scientists reports this week. This is the first time that a person with ...