Quadrupole Mass Spectrometers

With a real-time mass spectrometer developed by Fraunhofer researchers, it has become possible for the first time to analyze up to 30 components simultaneously from the gas phase and a liquid, including in-situ analysis. This sensitive measurement system is also suitable for the automated monitoring more

Thermo Fisher Scientific Inc. and Professor Bruno Domon, director of the new Luxembourg Clinical Proteomics unit (LCP), announced a collaboration to develop workflows that overcome current bottlenecks in biomarker discovery and assay development for clinical proteomics research. The LCP is funded by more

Thermo Fisher Scientific Inc. announced an alliance between its Biomarker Research Initiatives in Mass Spectrometry (BRIMS) Center and George Mason University's Center for Applied Proteomics and Molecular Medicine (CAPMM) to accelerate biomarker validation and forge new breakthroughs in early diseas more

Abstract High performance liquid chromatography coupled with time‐of‐flight mass spectrometry (HPLC‐TOF/MS) and high performance liquid chromatography ‐ triple quadrupole mass spectrometry (HPLC‐QQQ/MS/MS) were utilized to clarify the chemical constituents of Mahuang‐Fuzi‐Xixin Decoction. There more

Abstract Triple quadrupole mass spectrometers coupled with high performance liquid chromatography are workhorses in quantitative bioanalyses. They provide substantial benefits including reproducibility, sensitivity and selectivity for trace analysis. Selected reaction monitoring allows targeted more

Many protein kinases are activated through phosphorylation of an activation loop thereby turning on downstream signaling pathways. Activation of JAK2, a non‐receptor tyrosine kinase with an important role in growth factor and cytokine signaling, requires phosphorylation of the 1007 and 1008 tyrosy more