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445 Current news about the topic mutations


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More than the sum of mutations

165 new cancer genes identified with the help of machine learning


A new algorithm can predict which genes cause cancer, even if their DNA sequence is not changed. A team of researchers in Berlin combined a wide variety of data, analyzed it with “Artificial Intelligence” and identified numerous cancer genes. This opens up new perspectives for targeted cancer ...


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Why corona will not disappear and new vaccines will be needed


In a new research project, virologist Andreas Bergthaler is investigating how coronavirus mutations emerge in human hosts. He is seeking an explanation, among other things, for the sudden appearance of greatly mutated variants such as the ones dubbed British and South African. While the expert ...


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New single-cell analysis of leucemic stem cells

New method to distinguish between cancer stem cells, mature cancer cells and healthy tissue stem cells


A new method allows stem cells and cancer stem cells to be studied at the single cell level and the resulting cell clones to be traced directly. The method was developed by scientists from the Stem Cell Institute HI-STEM, the German Cancer Research Center (DKFZ), the European Molecular Biology ...


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SARS-CoV-2 mutations in competition

Accurately assess the transmissibility of new virus mutants


How dangerous are new mutations of the SARS-CoV-2 virus? An international team involving researchers from the Institute of Virology and Immunology (IVI) of the Federal Food Safety and Veterinary Office BLV and the University of Bern (Switzerland), the Centers for Disease Control and Prevention ...


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Unusual mutation causes defective sperm in boars

ETH researchers have found a gene mutation that causes the sperm of boars to immobilize


In pig farming, natural mating between a boar and a sow has become rare. It is much more common for sows to be artificially inseminated. This is more efficient and facilitates the breeding of pigs with desirable characteristics. Before sows can be artificially inseminated, veterinarians must ...


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New and highly efficient method for SARS-CoV-2 mutation analysis

Mutations can be assigned directly without any intermediate mathematical steps


The rapid spread of the newly emerging SARS-CoV-2 virus variant B.1.1.7 in Great Britain and other countries shows, changes in the genome of the SARS-CoV-2 virus can lead to new biological properties. Most of the approximately 12,000 mutations in the genome of the SARS-CoV-2 virus that have been ...


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New test to better assess environmental impact of substances

Researchers developed a test that investigates whether substances can cause inheritable changes in the genome of multicellular organisms such as insects


Researchers of the Senckenberg Biodiversity and Climate Research Centre and the LOEWE Centre for Translational Biodiversity Genomics hope to increase the reliability of environmental impact tests of substances. To this end, they developed a test that investigates whether substances can cause ...


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Spread of a novel SARS-CoV-2 variant across Europe in summer 2020

There is currently no evidence of this variant being more dangerous


Researchers from Basel and Spain have identified a novel SARS-CoV-2 variant that has spread widely across Europe in recent months, according to an un-peer-reviewed preprint released this week. While there is no evidence of this variant being more dangerous, its spread may give insights into the ...


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New tool helps to ‘spot the difference’ in genome organisation

This enables scientists to track down causes of diseases more quickly


The way DNA is organized in the cell nucleus is very important for the normal development and function of the cell. A mutation that affects the packaging of the genetic material in the cell nucleus can lead to developmental disorders or diseases such as cancer. A team of scientists from the Max ...


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The chameleon in the stomach

The bacterium Helicobacter pylori is linked to increased risk of stomach cancer, and is genetically highly variable


A new study by LMU researchers explores the role played by this diversity in the early phase of infection in adult humans. It is estimated that about half of the world’s population is infected with the bacterium Helicobacter pylori. Most primary infections occur in childhood. In many cases, it ...


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