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155 Current news about the topic fluorescence

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Staining Cycles with Black Holes

Ultrafast repeated staining and destaining of cell samples for tumor diagnostics

27-Mar-2020

In the treatment of tumors, microenvironment plays an important role. It often contains immune cells that are so changed that they promote tumor growth. In the journal Angewandte Chemie, scientists have introduced a method by which cell samples from tumors and their surroundings can rapidly ...

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Biologists make living sperm glow

16-Jan-2020

By applying a novel method, biologists at TU Dresden have successfully analysed the metabolism of intact tissues of the fruit fly using a label-free microscopy technique. They used the natural fluorescence of certain metabolic molecules and found that sperm, compared to other tissues, are highly ...

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How multicellular cyanobacteria transport molecules

16-Jul-2019

Researchers from ETH Zurich and the University of Tübingen have taken a high-resolution look at the structure and function of cell-to-cell connections in filamentous, multicellular cyanobacteria. This enables them to explain how these microorganisms regulate the transport of various substances ...

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Microglia Turned On

Visualizing microglia in brain tissue with a fluorescence turn-on substrate

20-May-2019

Part of the immune system in the brain is made up of so-called microglia cells. Korean and Singaporean researchers have now developed a fluorescent probe that specifically labels this type of macrophage. The cells were visualized in cell culture and in the live brains of rodents. As detailed in ...

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Tracking Small Things in Cells

Small and tunable fluorophores for the imaging of metabolites in living cells

02-May-2019

Living cells can react to disturbances with a changed metabolism, but direct observation of trafficking metabolites in live cells is difficult. An international team of scientists has now developed a class of remarkably small fluorophores called SCOTfluors. The dyes emit light in the visible to ...

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A new molecular player involved in T cell activation

13-Dec-2018

When bacteria or viruses enter the body, proteins on their surfaces are recognized and processed to activate T cells, white blood cells with critical roles in fighting infections. During T-cell activation, a molecular complex known as the microtubule-organizing center (MTOC) moves to a central ...

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"Waltzing" nanoparticles could advance search for better drug delivery methods

"Swirling and spinning" of therapeutic nanoparticles

15-Nov-2018

Indiana University researchers have discovered that drug-delivering nanoparticles attach to their targets differently based upon their position when they meet -- like ballroom dancers who change their moves with the music. The study is significant since the "movement" of therapeutic particles ...

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Novel quantum dots enhance cell imaging

31-Oct-2018

A team of researchers from the University of Illinois at Urbana-Champaign and Mayo Clinic have engineered a new type of molecular probe that can measure and count RNA in cells and tissue without organic dyes. The probe is based on the conventional fluorescence in situ hybridization (FISH) ...

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Know your enemy

An arsenal to fight antibiotic-resistant bacteria

11-Oct-2018

To fight your enemies, it helps to know their weaknesses. And, the more specific your knowledge, the easier it is to undermine their defenses. If your enemy sits safe behind a giant wall, for example, its valuable to know how your foe constructed it, what materials they used, and what cracks you ...

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GLUT5 fluorescent probe fingerprints cancer cells

23-Apr-2018

Determining the presence of cancer, as well as its type and malignancy, is a stressful process for patients that can take up to two weeks to get a diagnosis. With a new bit of technology--a sugar-transporting biosensor--researchers at Michigan Technological University hope to reduce that ...

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