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21 Current news about the topic creutzfeldt-jakob disease


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Impact of prion proteins on the nerves revealed for the first time

30-year-old research question finally answered


When prion proteins mutate, they trigger mad cow and Creutzfeldt-Jakob disease. Although they are found in virtually every organism, the function of these proteins remained unclear. Researchers from the University of Zurich and the University Hospital Zurich now demonstrate that prion proteins, ...


Prion disease detected soon after infection and in surprising place in mouse brains


Prion diseases - incurable, ultimately fatal, transmissible neurodegenerative disorders of mammals - are believed to develop undetected in the brain over several years from infectious prion protein. In a new study, National Institutes of Health (NIH) scientists report they can detect infectious ...


Finding a way forward in the fight against prion disease


Valerie Sim, an assistant professor in the University of Alberta's Faculty of Medicine & Dentistry, and Leonardo Cortez, a research associate in her lab, examining the use of two bile acids as possible therapeutic treatments for prion disease. The research found that ursodeoxycholic acid (UDCA) ...


Multitarget Drugs against Prion Diseases

Hybrid lipoic acid derivatives to attack prion disease on multiple fronts


The central nervous systems of humans and cattle alike are attacked by prions (abnormal insoluble amyloidogenic proteins) when they suffer from Creutzfeldt–Jakob disease (CJD) or bovine spongiform encephalopathy (BSE). This causes a steady deterioration of neurological function and ultimately ...


BSE pathogens can be transmitted by air


Airborne prions are also infectious and can induce mad cow disease or Creutzfeldt-Jakob disorder. This is the surprising conclusion of researchers at the University of Zurich, the University Hospital Zurich and the University of Tübingen. They recommend precautionary measures for scientific labs, ...


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Scientists develop new method to identify glycosylated proteins


Various processes in our body are controlled by subsequent changes of proteins. Therefore, the identification of such modifications is essential for the further exploration of our organism. Now, scientists of the Max Planck Institute of Biochemistry in Martinsried, Germany, have made a crucial ...


Prion study reveals first direct information about the protein’s molecular structure


A collaboration between scientists at Vanderbilt University and the University of California, San Francisco has led to the first direct information about the molecular structure of prions. In addition, the study has revealed surprisingly large structural differences between natural prions and the ...


Prometic obtains controlling stake in Pathogen Removal and Diagnostic Technologies Inc.

Non Cash Transaction results in ProMetic increasing its holding of common stock from 26% to 77%


ProMetic Life Sciences Inc. announced that it has finalized its intended transaction with the American Red Cross (ARC) to acquire, in a non-cash transaction, its common stock holding in Pathogen Removal and Diagnostic Technologies Inc. (PRDT). The transaction, originally announced in April ...


Amorfix Test for vCJD achieves 100% specificity on 20,000 blood donations in France


Amorfix Life Sciences announced it has tested 20,000 blood donations in France using its EP-vCJD™ blood screening test as part of a large-scale study to demonstrate the feasibility of routine testing of blood donations for vCJD (variant Creutzfeldt-Jakob disease). At the UK specification of a ...


Amorfix awarded "Life Science Company of the Year" for moving innovative products into commercialization


Amorfix Life Sciences Ltd. has been selected as the inaugural recipient of the “Life Science Company of the Year” by The Biotechnology Initiative. Amorfix was selected because of its pioneering approaches to innovative diagnostic and therapeutic products for brain-wasting diseases, including ...


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