Coronaviruses - 24 News by Charité
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How COVID-19 affects the brain
Neurological symptoms apparently not a result of SARS-CoV-2 infection of the brain
19-Feb-2024 - Scientists still are not sure how neurological symptoms arise in COVID-19. Is it because SARS-CoV-2 infects the brain? Or are these symptoms the result of inflammation in the rest of the body? A study by Charité – Universitätsmedizin Berlin has now produced evidence to support the latter theory. ...
Coronavirus vaccination: body builds immune memory in organs
Memory cells in the liver, kidneys, and lungs
13-Oct-2023 - One shot in the arm, and the whole body is protected. But how? For one thing, the immune system produces antibodies and cells that patrol the entire organism by traveling through the bloodstream. For another, as shown by a recent Charité – Universitätsmedizin Berlin study of the mRNA coronavirus ...
Nasal vaccine to prevent COVID-19 passes first tests
Better than conventional vaccines: Protection at the site of infection
05-Apr-2023 - Since the beginning of the COVID-19 pandemic, researchers have been working on mucosal vaccines that can be administered through the nose. Now, scientists in Berlin have developed a live attenuated vaccine for the nose. Coronaviruses spread primarily through the air. When infected people speak, ...
Where did Omicron come from?
Study published in Science sheds light on the origins of the SARS-CoV-2 variant
06-Dec-2022 - First discovered a year ago in South Africa, the SARS-CoV-2 variant later dubbed “Omicron” spread across the globe at incredible speed. It is still unclear exactly how, when and where this virus originated. Now, a study published in the journal Science by researchers from Charité – ...
Corona: New Insights into Antibody Response against Viral Variants
Cross-reactivity could prove to be an important aspect of future vaccinations
27-Jan-2022 - In the journal Science, researchers from Charité – Universitätsmedizin Berlin and Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) present new findings on the immune response against the coronavirus SARS-CoV-2. Their study is based on investigations of antibodies elicited by infection ...
Machine learning model uses blood tests to predict COVID-19 survival
Levels of 14 proteins in the blood of critically ill COVID-19 patients are associated with survival
21-Jan-2022 - A single blood sample from a critically ill COVID-19 patient can be analyzed by a machine learning model which uses blood plasma proteins to predict survival, weeks before the outcome, according to a new study published in the open-access journal PLOS Digital Health by Florian Kurth and Markus ...
The fatal role of T cells in COVID-19
Safety mechanism is put out of action
06-Jan-2022 - Scientists from the Berlin Institute of Health at Charité (BIH), together with colleagues from Charité – Universitätsmedizin Berlin and the university hospitals in Bonn and Aachen, have found a type of immune cells that is particularly active in severely ill COVID-19 patients. The CD16 positive T ...
SARS-CoV-2 disrupts timing of immune response
Researchers anticipate that the timely inhibition of TGFβ could prevent progression to severe COVID-19
27-Oct-2021 - Once an infection is under control, the body normally uses a biochemical messenger known as TGFβ to downgrade its immune response. In severe COVID-19, however, this messenger is released at the very beginning of the infection, thus blocking the early control of the pathogen by the innate immune ...
COVID-19: What is driving the escalating hyperinflammation
Study published in Nature suggests novel treatment option
15-Sep-2021 - The severity of COVID-19 is not determined solely by the SARS-CoV-2 virus itself; rather, it is the primary result of a dysregulated immune response. A team of researchers from Charité – Universitätsmedizin Berlin, the Max-Delbrück-Center for Molecular Medicine (MDC), Johannes Kepler University ...
Prior exposure to common cold coronaviruses enhances immune response to SARS-CoV-2
03-Sep-2021 - Researchers from Charité – Universitätsmedizin Berlin, the Berlin Institute of Health at Charité (BIH) and the Max Planck Institute for Molecular Genetics (MPIMG) have shown that certain immune cells, which are found in people previously exposed to common cold coronaviruses, enhance the body’s ...
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