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Mutations

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  • Chromothripsis in human cancer

    Researchers at Harvard Medical School and EMBL-EBI have carried out the largest analysis across cancer types of the newly discovered mutational phenomenon chromothripsis. This study is the largest of its kind to date, containing whole-genome sequencing (WGS) data from over 2600 tumours spanning 38 d more

  • New insights into the evolution of proteins

    How do bacteria manage to adapt to synthetic environmental toxins and, for example, to even develop strategies for using a pesticide and chemical warfare agent as food within less than 70 years? The evolutionary adaptations underlying such processes have now been studied in detail by an internationa more

  • BAFfling cancer growth strategies: new targets for chromatin remodeling mutations identified

    More than one-fifth of all human cancers harbor mutations in one of the members of the BAF chromatin remodeling complex. Deep biochemical and epigenomic characterization of a cell line panel comprehensively representing all these mutations enabled researchers at the CeMM Research Center for Molecule more

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Definition

Mutation

Mutation In biology , mutations are changes to the base pair sequence of the genetic material of an organism. Mutations can be caused by copying errors in the genetic material during cell division , by exposure to ultraviolet or ionizing ra ... more

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