Molecular Diagnostics

Companies Molecular Diagnostics

oncgnostics GmbH, Germany

The oncgnostics GmbH, a spin-off of the University Hospital Jena, is a company working on molecular diagnostics with main focus on the development of in-vitro diagnostics based on epigenetic biomarkers. oncgnostics GmbH is working according to ISO 13485 standards in research, development, production more

News Molecular Diagnostics

• Smallest life forms have smallest working CRISPR system

  An ancient group of microbes that contains some of the smallest life forms on Earth also has the smallest CRISPR gene-editing machinery discovered to date. The peewee protein machinery, dubbed Cas14, is related to but one-third the size of the Cas9 protein, the business end of the revolutionary gene more

• Sensitive new assay detects hepatitis B infection in single liver cells and serum

  Chronic hepatitis B virus (HBV) can progress to cirrhosis and hepatocellular carcinoma (HCC). A study describes a new HBV assay that offers advantages over currently used methods because it has the capability to detect closed circular DNA (cccDNA) in serum, single cells, and preserved tissue samples more

• QIAGEN acquires Spanish diagnostics start-up company

  QIAGEN N.V. announced it has entered into an agreement to acquire STAT-Dx, a privately-held company developing the next generation of multiplex diagnostics for one-step, fully integrated molecular analysis of common syndromes using a novel system based on real-time PCR technology and proven QIAGEN c more

White papers Molecular Diagnostics

• Minimum Space Requirement – Maximum Detection Efficiency
  

  Learn how the multispectral PixelSensor™ is revolutionizing sophisticated point-of-care testing in healthcare more

• Direct Eubacterial PCR Diagnosis of Primary Sterile Body Fluids and Tissues
  

  Culture-inde¬pend¬ent molecular identification is a straight forward approach for the rapid pathogen identification, including fastidious and antibiotic-inhibited microorganisms. CE-IVD UMD-Universal has been evaluated using primary sterile body flui more

Publications Molecular Diagnostics

• Toward dynamic structural biology: Two decades of single-molecule Förster resonance energy transfer

  Classical structural biology can only provide static snapshots of biomacromolecules. Single-molecule Förster resonance energy transfer (smFRET) paved the way for studying dynamics in macromolecular structures under biologically relevant conditions. Since its first implementation in 1996, smFRET ex more

• Coexistence of mutations in keratin 10 (KRT10) and the mitochondrial genome in a patient with ichthyosis with confetti and Leber's hereditary optic neuropathy

  Ichthyosis with confetti (IWC) is a severe congenital genodermatosis characterized by ichthyosiform erythroderma since birth and confetti‐like spots of normal skin appearing in childhood as a results of revertant mosaicism. This disorder is caused by mutations in KRT10 or KRT1 genes. We report a more

• Effect of ageing and Single Nucleotide Polymorphisms associated with risk of aggressive prostate cancer in a New Zealand population

  Prostate cancer is one of the most significant male health concerns worldwide, various researchers carrying out molecular diagnostics have indicated that genetic interactions with biological and behavioral factors play an important role in the overall risk and prognosis of this disease. Single nucle more