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Idiopathic Pulmonary Fibrosis

News Idiopathic Pulmonary Fibrosis

  • New lung 'organoids' in a dish mimic features of full-size lung

    New lung "organoids"--tiny 3-D structures that mimic features of a full-sized lung--have been created from human pluripotent stem cells by researchers at Columbia University Medical Center (CUMC). The team used the organoids to generate models of human lung diseases in a lab dish, which could be use more

  • Pulmonary fibrosis culprits

    Isoketals (IsoKs) – highly reactive compounds formed when membrane lipids are attacked by free radicals – are emerging as a mechanistic link between pathogenic reactive oxygen species and disease progression. However, the identity of IsoK-modified proteins and whether isoketal generation is subject more

  • Bristol-Myers Squibb enters agreement to acquire Promedior, Inc.

    Bristol-Myers Squibb Company and Promedior, Inc. announced that the companies have entered into an agreement that grants Bristol-Myers Squibb an exclusive right to acquire Promedior and gain worldwide rights to its lead asset PRM-151, a recombinant form of human pentraxin-2 protein in Phase 2 develo more

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Videos Idiopathic Pulmonary Fibrosis

New Lung “Organoids” In a Dish Mimic Features of Full-Size Lung

Researchers at Columbia University Medical Center have developed three-dimensional lung bud "organoids" from human pluripotent stem cells. The "mini organs" could be used to model lung diseases such as pulmonary fibrosis and respiratory syncytial virus infection.The research was carried out in t ... more

Events Idiopathic Pulmonary Fibrosis

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Phenotypic Screening - Complex and Disease Relevant Human Primary Cell Assays

                        In the past few years, there has been a revival of phenotypic screening for hit discovery and profiling. It is generally accepted that overexpression of targets in heterologous systems has a risk of creating functional artefacts, and in principle, such an assay is single-tar

Publications Idiopathic Pulmonary Fibrosis

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Market studies Idiopathic Pulmonary Fibrosis

  • Idiopathic Pulmonary Fibrosis – Pipeline Review, H1 2012

    Introduction Global Markets Direct’s, 'Idiopathic Pulmonary Fibrosis - Pipeline Review, H1 2012', provides an overview of the Idiopathic Pulmonary Fibrosis therapeutic pipeline. This report provides information on the therapeutic development for Idiopathic Pulmonary Fibrosis, complete with latest more

  • Rare and Niche Diseases Catalyst Monitor - Key Event Analysis H1 2012

    Introduction GlobalData’s new report, "Rare and Niche Diseases Catalyst Monitor - Key Event Analysis H1 2012" takes a look at rare and niche diseases, which are an area of intense interest in the global biopharmaceutical industry today. The passage of the Orphan Drug Act in the United States in 19 more

  • Sweden Pharmaceuticals and Healthcare Report Q4 2012

    BMI Industry View BMI View: Overall pharmaceuticals growth in Sweden will remain low and even decline over the short term due to patent expiration and cost containment policies, resulting in opportunities for generic drugmakers. Despite the low growth, the increasingly ageing population in Sweden me more

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Definition

Idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis Idiopathic Pulmonary Fibrosis (IPF), also known as Cryptogenic fibrosing alveolitis, is a chronic progressive interstitial lung disease of unknown etiology. It is one of the two classic interstitial lung diseases ... more

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