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Yt antigen system



The Yt antigen system (also known as Cartwright) is present on the membrane of red blood cells and helps determine a person's blood type. The antigens are found on the protein acetylcholinesterase, an enzyme which helps break down acetylcholine.[1] The Yt system features two alleles, Yt(a) and Yt(b). Antibodies against the Yt system can lead to transfusion reactions such as hemolytic anemia.

Additional recommended knowledge

References

Online 'Mendelian Inheritance in Man' (OMIM) 112100 - OMIM page on Yt antigen

  1. ^ Bartels CF, Zelinski T, Lockridge O. Mutation at codon 322 in the human acetylcholinesterase (ACHE) gene accounts for YT blood group polymorphism. Am J Hum Genet. 1993 May;52(5):928-36. PMID 8488842
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Yt_antigen_system". A list of authors is available in Wikipedia.
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