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Vaccine Safety Datalink



The Vaccine Safety Datalink Project (VSD) was established in 1990 by the United States Centers for Disease Control and Prevention (CDC) to study the adverse side effects of vaccines.

Four large health maintenance organizations, including Kaiser Permanente, were initially recruited to provide the CDC with medical data on vaccination histories, health outcomes, and subject characteristics. The VSD database contains data compiled from surveillance on more than seven million Americans, including about 500,000 children from birth through age six years (2% of the U.S. population in this age group).[1]

The VSD data-sharing program is now being administered by the National Center for Health Statistics Research Data Center. The data sharing guidelines have been revised to include comments from interested groups as well as recommendations from the Institute of Medicine (IOM).

Data from the Vaccine Safety Datalink Project have been utilized to address a number of vaccine safety concerns; examples include a study clarifying the risk of anaphylaxis after vaccine administration[2] and several studies examining the link between thimerosal-containing vaccines and autism.[3][4][5][6]

Notes

  1. ^ Chen RT, Glasser JW, Rhodes PH, et al (1997). "Vaccine Safety Datalink project: a new tool for improving vaccine safety monitoring in the United States. The Vaccine Safety Datalink Team". Pediatrics 99 (6): 765–73. PMID 9164767.
  2. ^ Bohlke K, Davis RL, Marcy SM, et al (2003). "Risk of anaphylaxis after vaccination of children and adolescents". Pediatrics 112 (4): 815–20. PMID 14523172.
  3. ^ Geier MR, Geier DA (Spring, 2003). "Thimerosal in Childhood Vaccines, Neurodevelopment Disorders and Heart Disease in the United States" (PDF). Journal of American Physicians and Surgeons 8 (1).
  4. ^ Geier DA, Geier MR (Spring, 2006). "Early Downward Trends in Neurodevelopmental Disorders Following Removal of Thimerosal-Containing Vaccines" (PDF). Journal of American Physicians and Surgeons 11 (1).
  5. ^ Verstraeten T, Davis RL, DeStefano F, et al (2003). "Safety of thimerosal-containing vaccines: a two-phased study of computerized health maintenance organization databases". Pediatrics 112 (5): 1039–48. PMID 14595043.
  6. ^ Thompson WW, Price C, Goodson B, et al (2007). "Early thimerosal exposure and neuropsychological outcomes at 7 to 10 years". N. Engl. J. Med. 357 (13): 1281–92. doi:10.1056/NEJMoa071434. PMID 17898097.
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Vaccine_Safety_Datalink". A list of authors is available in Wikipedia.
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