To use all functions of this page, please activate cookies in your browser.
With an accout for my.bionity.com you can always see everything at a glance – and you can configure your own website and individual newsletter.
- My watch list
- My saved searches
- My saved topics
- My newsletter
The Correlation Between Relatives on the Supposition of Mendelian Inheritance
"The Correlation Between Relatives on the Supposition of Mendelian Inheritance" is a scientific paper by R.A. Fisher which was published in the Philosophical Transactions of the Royal Society of Edinburgh in 1918, (volume 52, pages 399–433). In it, Fisher puts forward a genetic model that shows that continuous variation amongst characters could be the result of Mendelian inheritance. The paper also contains the first use of the term variance.
Additional recommended knowledge
Mendelian genetics was rediscovered in 1900. However, there were differences of opinion as to the variation that natural selection acted upon. The biometric school, led by Karl Pearson followed Darwin's idea that small differences were important for evolution. The Mendelian school, led by William Bateson, however thought that Mendel's work gave an evolutionary mechanism with large differences.
Joan Box, Fisher's biographer and daughter states in her book that Fisher, then a student, had resolved this problem in 1911.
Fisher had originally submitted his paper (then entitled "The correlation to be expected between relatives on the supposition of Mendelian inheritance") to the Royal Society, to be published in the Transactions of the Royal Society of London. The two referees, the biologist R. C. Punnett and the statistician Karl Pearson, believed that the paper contained areas they were unable to judge, due to lack of expertise, and expressed some reservations. Though the paper was not rejected, Fisher carried a feud with Pearson from 1917 on, and sent the paper instead to the Royal Society of Edinburgh, which published it in its Transactions.
Fisher defines his new term of variance, as the square of the standard deviation, because of the manner in which variances of independent random variables may be added. He notes the continuous variation in human characters.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "The_Correlation_Between_Relatives_on_the_Supposition_of_Mendelian_Inheritance". A list of authors is available in Wikipedia.|