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Penitrem A (tremortin) is a fungal neurotoxin found on ryegrass. It is produced by certain species of Aspergillus, Claviceps, and Penicillium. It inhibits potassium channels in smooth muscles. The maxi-channels targeted have their highest density in the cerebellar Purkinje cells.
It causes a stagger in horses and cattle.
Additional recommended knowledge
Stages of toxicity
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Penitrem_A". A list of authors is available in Wikipedia.|