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Pangamic acid



Pangamic acid
IUPAC name 6-(2-Dimethylamino-acetoxy)-2,3,4,5-tetrahydroxy-hexanoic acid
Other names Vitamin B15
Identifiers
CAS number 20858-86-0
SMILES OC([C@H](O)[C@@H](O)[C@H](O)[C@H](O)COC(CN(C)C)=O)=O
Properties
Molecular formula C10H19NO8
Molar mass 281.26
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)
Infobox disclaimer and references

Pangamic acid is an ester derived from gluconic acid and dimethylglycine.[1] It was first isolated by Ernst T. Krebs from apricot kernels,[2] and has since been identified in some foods such as pulses.[3]

Additional recommended knowledge

Pangamic acid is also known as vitamin B15, but it is not widely accepted as a vitamin because it has not been shown to be essential in the human diet, and a deficiency in consumption of pangamic acid is not associated with any disease.[4]

The calcium salt of pangamic acid, calcium pangamate, is used as a mineral supplement.

References

  1. ^ Recent data on the structure of pangamic acid (vitamin B15). Telegdy Kovats, Laszlo; Berndorfer-Kraszner, Eva; Juhasz, Agnes; Gabor, Tamas. Acta Alimentaria Academiae Scientiarum Hungaricae (1976), 5(3), 281-8.
  2. ^ KREBS E T Sr; KREBS E T Jr; BEARD H H; MALIN R; HARRIS A T; BARTLETT C L Pangamic acid sodium: a newly isolated crystalline water-soluble factor; a preliminary report. International record of medicine and general practice clinics (1951), 164(1), 18-23.
  3. ^ Singh, Jagdev; Handa, Mrs. Geeta; Nandi, L. N.; Manavalan, R.; Atal, C. K. D-Gluconodimethylaminoacetic acid from natural sources. Indian Drugs (1983), 20(5), 185-9.
  4. ^ "Vitamin B15 - Pangamic Acid", Elson M. Haas M.D.
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Pangamic_acid". A list of authors is available in Wikipedia.
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