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PAS diastase



In histology, PAS diastase is stain to ellucidate gastric duodenal metaplasia in duodenal adenomas.[1] More generally, PAS diastase is a histological stain often used as a negative control for glycogen. Diastase is an enzyme that breaks down glycogen and PAS is a stain that typically gives a magenta colour in the presence of glycogen. When the two are used together a light pink colour replaces the deep magenta. Differences in the intensities of the two stains (PAS and PAS-D) can be attributed to different glycogen concentrations and can be used to semiquantify glycogen in samples.

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References

  1. ^ Rubio CA (2007). "Gastric duodenal metaplasia in duodenal adenomas". J. Clin. Pathol. 60 (6): 661-3. doi:10.1136/jcp.2006.039388. PMID 16837629.
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "PAS_diastase". A list of authors is available in Wikipedia.
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