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A lysogen or lysogenic phage is a phage that can exist as a prophage within its host organism. A prophage is the phage DNA in it's dormant state, and is either integrated into the host bacteria's chromosome or more rarely exists as a stable plasmid within the host cell. The prophage expresses gene(s) that repress the phage's lytic action, and the phage enters the lytic cycle when this suppression is disrupted. Currently a variety of studies are being conducted to see whether other genes are active during lysogeny, examples of which include phage-encoded tRNA and virulence genes.
Additional recommended knowledge
Alternatively, lysogen can refer to a bacteria strain that carries a prophage.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Lysogen". A list of authors is available in Wikipedia.|