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Hertwig's epithelial root sheath
Additional recommended knowledge
The Hertwig's epithelial root sheath (frequently abbreviated as "HERS") is a proliferation of epithelial cells located at the cervical loop of the enamel organ in a developing tooth. Hertwig's epithelial root sheath initates the formation of dentin in the root of a tooth by causing the differentiation of odontoblasts from the dental papilla. The root sheath eventually disintegrates, but residual pieces that do not completely disappear are seen as epithelial cell rests of Malassez (ERM).
Evolution of HERS
Hertwig's epithelial root sheath was not discovered in any mammalian species. Instead this epithelial structure was discovered by Oskar Hertwig in 1874 in an amphibian. While in mammalian the HERS is rather a transient structure in amphibians it is more or less a permanent one. Here the root epithelium does not fenestrate like in mammalians. Within vertebrates 3 distinct stages of HERS development can be observed.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Hertwig's_epithelial_root_sheath". A list of authors is available in Wikipedia.|