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Glucagon rescue is the emergency injection of glucagon in case of severe diabetic hypoglycemia. It is needed during seizures and/or unconsciousness by an insulin user who is unable at that point to help themself. Glucagon will facilitate the release of stored glucose back into the bloodstream, raising the blood glucose level.
Rescue has been simplified by the development of the glucagon emergency kit, consisting of:
At the first signs of hypoglycemia, an insulin user should treat it immediately by consuming carbohydrate to restore blood glucose to safe levels (thereby preventing progression to severe hypoglycemia). However, not all insulin users can feel and recognize the early signs, particularily when sleeping. This can quickly lead to an emergency resulting in unconsciousness, inability to swallow, seizures, and in extreme cases death. In the past, treatment consisted of intravenous delivery of dextrose (glucose) usually in the emergency room; however, the delay in treatment due to emergency response and transport to a medical facility is life threatening.
The glucagon emergency kit facilitates rapid rescue by a simple injection, which does not require medical expertise, and can be done quickly and easily outside of a medical facility.
Additional recommended knowledge
Manufacturers of Glucagon Rescue Kits
"Glucagon Emergency Kit" from Eli Lilly and Company
"GlucaGen Hypo Kit" from Novo Nordisk
Vials of GlucaGen from Bedford Laboratories
Glucagon Rescue Instructions
The instructions for using the emergency glucagon rescue kit can be simplified to the 4 essential steps as shown in the pictures inside the orange box cover.
The steps to perform glucagon rescue and perhaps save a life are few and simple. However, the instructions that are supplied with the glucagon emergency rescue kit are long, and potentially complicated to use.
There are three counter-productive issues with the instructions:
This is avoidable because the 4 necessary steps, as illustrated in instructional pictures inside the top cover of the plastic box, do not require additional detail. The kit has been carefully designed to facilitate rescue outside of a medical facility by non-medical personnel. So while the information is helpful to the pharmacist and in prior training for glucagon administration, perhaps the instructions should just be removed by the user before carrying the kit in a situation where it might possibly be needed for them.
Politics of Glucagon Rescue
Public awareness of other forms of life saving measures has increased dramatically in the past, such as:
However, despite public relations to increase the awareness of the life saving capability of glucagon rescue, it is still largely unknown by the general public. An unfortunate example is seen in public school policy and some teacher's union contracts in the U.S., which require that union teachers shall not be allowed to deliver glucagon or even be trained in administration of glucagon.    This can only be due to the ignorance of glucagon as a life saving measure, as it would obviously be absurd to prohibit training and delivery of CPR or any other life saving first aid in a public school.
Many insulin users now carry the kit with them at all times. It is imperative that the public learn to search an unconscious person for an identification of a medical alert: and upon finding information about diabetes or insulin use, the public must then learn to search the unconscious person for a glucagon emergency rescue kit and use it.
Glucagon "Mini-dose" Instruction
The purpose of the "mini-dose" is to avoid an emergency condition that may require glucagon rescue. This might be needed in cases such as when a diabetic child is injected with insulin before breakfast, eats, and then vomits and cannot eat again: with the injected insulin working its way into the bloodstream and no carbohydrate to balance, there may soon be a hypoglycemic emergency.
To avoid severe hypoglycemia (or alternatively avoid a trip to the hospital for intravenous glucose), the glucagon from the emergency rescue kit can be used in a measured dose to maintain the blood glucose level. Instead of the glucagon emergency syringe and its large bore needle, a standard U-100 insulin syringe can be used. The recommended dose is:
The mini-dose treatment should be repeated as necessary to maintain blood sugar until food can be eaten.
Medical studies have shown that the mini-dose rescue is tolerated well and effective.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Glucagon_rescue". A list of authors is available in Wikipedia.