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Diphthamide



Diphthamide
IUPAC name 2-Amino-3-[2-(3-carbamoyl-3-trimethylammonio-propyl)-3H-imidazol-4-yl]propanoate
Identifiers
CAS number 75645-22-6
PubChem 6438375
SMILES C[N+](C)(C)C(CCC1=NC=C(N1)CC(C(=O)[O-])N)C(=O)N
Properties
Molecular formula C13H23N5O3
Molar mass 297.35 g mol-1
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)
Infobox disclaimer and references

Diphthamide is a modified histidine amino acid found in eukaryotic elongation factor 2 (eEF-2). It is ADP-ribosylated by diphtheria toxin, which renders the elongation factor inactive.

 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Diphthamide". A list of authors is available in Wikipedia.
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