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Diff-Quik® is a commercial stain commonly used in histological staining to rapidly stain and differentiate a variety of smears, commonly blood and vaginal smears. It is based on a modification of the Wright Giemsa stain pioneered by Bernard Witlin in 1970. It has advantages over the older Wright Giemsa staining technique, as it reduces the 4 minute process into a simplified 15 second operation, and allows for selective increased eosinophilic or basophilic staining depending upon the time the smear is left in the staining solutions.


The Diff-Quik stain consists of 3 solutions:


Structure Colour
Erythrocytes Pink/yellowish red
Platelets Violet/purple granules
Neutrophils Blue nucleus, pink cytoplasm, violet granules
Eosinophils Blue nucleus, blue cytoplasm, red granules
Basophils Purple/dark blue nucleus, violet granules
Monocyte Violet nucleus, light blue cytoplasm
Bacteria Blue


This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Diff-Quik". A list of authors is available in Wikipedia.
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