Dermatopathia pigmentosa reticularis

Dermatopathia pigmentosa reticularis (DPR) is a form of a rare sex-linked ectodermal dysplasia congenital disorder that afflicts females. Symptoms include lack of sweat glands, thin hair, brittle nails, mottled skin, and lack of fingerprints.

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DPR is comparable to Naegeli syndrome, both of which is caused by a specific defect in the keratin 14 protein.