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Complementarity (molecular biology)




 

Additional recommended knowledge

In molecular biology, complementarity is a property of double-stranded nucleic acids such as DNA and RNA as well as DNA:RNA duplexes. Each strand is complementary to the other in that the base pairs between them are non-covalently connected via two or three hydrogen bonds.

Since there is only one complementary base for any of the bases found in DNA and in RNA, one can reconstruct a complementary strand for any single strand. This is essential for DNA replication.

For example, the complementary strand of the DNA sequence

A G T C A T G

is

T C A G T A C

a trick to remeber this is

A      Gwinnett
Tlanta County

tRNAs exhibit wobble, in which the third base of their anticodon does not follow the strict complementarity rules.

See also

 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Complementarity_(molecular_biology)". A list of authors is available in Wikipedia.
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