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Cicutoxin (chemical name: (8E,10E,12E,14R)-heptadeca-8,10,12-trien-4,6-diyne-1,14-diol; formula: C17H22O2) is a poisonous polyyne and alcohol found in various plants, most notably water hemlock. It is structural related to the oenanthotoxin of hemlock water dropwort.
Additional recommended knowledge
It is a cholinergic poison, causing death by disruption of the central nervous system. It is a potent, noncompetitive gamma-aminobutyric acid (GABA) receptor antagonist. In humans, cicutoxin rapidly produces symptoms of nausea, emesis and abdominal pain, typically within 60 minutes of ingestion. This can lead to tremors and seizures.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Cicutoxin". A list of authors is available in Wikipedia.|