The Bioinformatic-Harvester is a bioinformatic meta search engine at KIT Karlsruhe Institute of Technology for genes and protein-associated information. Harvester currently works for human, mouse, rat, zebrafish, drosophila and arabidopsis thaliana based information. Harvester cross-links >28 popular bioinformatic resources and allows cross searches. A ranking system similar to Google pagerank sorts the search results and displays the more relevant information. Harvester serves 10.000s of pages every day to scientists and physicians.
Harvester collects information from protein and gene databases along with information from so called "prediction servers." Prediction server e.g provide online sequence analysis for a single protein. Harvesters search index is based on the IPI and UniProt protein information collection. The collections consists of:
~68.000 human, ~53.000 mouse, ~42.000 rat, ~51.000 zebrafish, ~35.000 arabidopsis and ~33.000 drosophila protein pages, which are curated and updated on a regular basis.
Homologene, compares proteins from different species
gfp-cdna, protein localisation with fluorescence microscopy
International Protein Index (IPI).
Databases rich in graphical elements
...are not collected, but crosslinked via iframes. Iframes are transparent windows within a HTML pages. The iframe windows allows up-to-date viewing of the "iframed," linked databases. Several such iframes are combined on a Harvester protein page. This method allows convenient comparison of information from several databases.
NCBI-BLAST, an algorithm for comparing biological sequences NCBI.
Ensembl, automatic gene annotation. EMBL-EBI and Sanger-Institute
FlyBase is a database of model organism Drosophila melanogaster.
GoPubMed is a knowledge-based search engine for biomedical texts.
iHOP, information hyperlinked over proteins via gene/protein synonyms