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In biology, autologous refers to cells, tissues or even proteins that are reimplanted in the same individual as they come from. Bone marrow, skin biopsy, cartilage, and bone can be used as autografts.
Additional recommended knowledge
In contrast, cells or tissues transplanted from a different individual are referred to as allogeneic or as an allograft.
Autologous blood donation
The advantages of Autologous blood donation are:
The primary disadvantages are the significantly higher cost and the need to make all necessary arrangements well in advance. Autologous blood is stored at one specific hospital clearly labelled for use by one specific patient; if it is not used by that patient, it is discarded.
There is also a risk that, in an emergency or if more blood is required than has been set aside in advance, the patient could still be exposed to donor blood instead of autologous blood. Autologous donation is also not suitable for patients who are medically unable to or not advised to give blood, such as cardiac patients or small children and infants.
In orthopaedic medicine, bone graft can be sourced from a patient's own bone in order to fill space and produce an osteogenic response in a bone defect. However, due to the donor-site morbidity associated with autograft, other methods such as bone allograft and bone morphogenetic proteins and synthetic graft materials are often used as alternatives.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Autologous". A list of authors is available in Wikipedia.|