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Additional recommended knowledge
Anaphylatoxin is able to trigger degranulation of (release of substances from) mast cells or basophils, which is an important part of the immune system in all kinds of inflammation and especially as part of defense against parasites. If the degranulation is too strong, it can cause allergic reactions.
Anaphylatoxins indirectly mediate:
Although some drugs (morphine, codeine, synthetic ACTH) and some neurotransmitters (norepinephrine, substance P) are important mediators of degranulation of mast cells or basophils, they are generally not called anaphylatoxins. This term is reserved only for fragments of the complement.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Anaphylatoxin". A list of authors is available in Wikipedia.|