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Coronaviruses cause a wide variety of diseases - from mild colds to severe acute respiratory syndrome (SARS). This virus family of Coronaviridae includes many different pathogens, such as the SARS and MERS viruses. The current coronavirus epidemic is now spreading with enormous momentum from the Chinese city of Wuhan. This new, previously unknown pathogen bears the name SARS-CoV-2.
Delivers highly purified viral RNA for use in PCR-based applications ✓ Automation-friendly ✓ Complete research and detection workflows more
Extraction procedure delivering inhibitor-free viral DNA/RNA for highly sensitive downstream detection ✓ Consistent Results with guided touchscreen operation more
Fluoxetine, a common antidepressant, inhibits the SARS-CoV-2 coronavirus in cell cultures and in preparations from human lung tissue. This was demonstrated by researchers at Julius-Maximilians-Universität (JMU) Würzburg in the summer of 2020. However, the mechanism of this inhibition was utterly unc more
A large number of people are currently contracting COVID-19. Fortunately, most of them are experiencing only mild symptoms, largely thanks to the high vaccination rate. However, in some individuals the disease takes a much more severe cause and our understanding about the underlying reasons is still more
People who have often been infected by common cold viruses – which also belong to the coronaviruses – are not better protected against COVID-19, neither after infection with SARS-CoV-2 nor after vaccination. "We already showed in 2020 that earlier exposure to common cold viruses does not provide pro more
A vaccine is a type of treatment aimed at stimulating the body’s immune system to fight against infectious pathogens such as bacteria and viruses. The more
Immunity testing against Covid-19 without false-positives is possible using the right combi-nation of optimized solutions for ELISA protocol. more
Pathogens are continuously emerging and evolving. Addressing the threat of new and potentially life-threatening pathogens requires deep understanding more
The red-hot topic of SARS-CoV-2/COVID-19 diagnostics, especially using antibodies, is discussed in this webinar of Prof. Dr. Jörg Hollidt, chariman of the board of DiagnostikNet Berlin-Brandenburg. Which tests are available on the market? What weaknesses and strenghts do they have? What does the Dia more
Key to SARS-CoV-2 therapeutic development is unraveling the mechanisms driving high infectivity. SARS-CoV-2 is decorated by multiple copies of a glycoprotein,called Spike, which is key to infectivity. Using cryo-electron microscopy, we discovered a potentially druggable pocket within the SARS-CoV-2 more
How do you fight something you can’t see? That’s the question when it comes to the coronavirus crisis which currently has many of us holed up at home. Physical distancing is one important answer to preventing the spread of the virus, as avoiding catching it in the first place stops you from spreadin more
Across the world, countries are scrambling to increase their testing capacity for the virus — how are these tests carried out and how do they work? more
By now, we’re all familiar with the image of coronavirus. The spikey blob peppers news websites, looms behind reporters during bulletins and frequently punctuates your Twitter doom-scrolling. More recently, the news accompanying this image has taken a positive turn, with promising results from the C more
Coronaviruses exhibit a propensity for interspecies transmission, with SARS- and MERS-coronaviruses as notable examples. Cross-species transmission by coronaviruses is foremost determined by the virus’ ability to bind receptors of new hosts. We here report that the recently identified, yet globally more
Viruses, Vol. 10, Pages 93: MERS-CoV: Understanding the Latest Human Coronavirus Threat Viruses doi: 10.3390/v10020093 Authors: Aasiyah Chafekar Burtram Fielding Human coronaviruses cause both upper and lower respiratory tract infections in humans. In 2012, a sixth human coronavirus more
The tremendous pandemic potential of coronaviruses was demonstrated twice in the past few decades by two global outbreaks of deadly pneumonia. The coronavirus spike (S) glycoprotein initiates infection by promoting fusion of the viral and cellular membranes through conformational changes that remain more
Coronavirus Coronavirus is a genus of animal virus belonging to the family Coronaviridae . Coronaviruses are enveloped virus es with a positive-sense single-stranded RNA genome and a helical symmetry. The genomic size of coronaviruses ranges ... more
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