Colorectal Cancer

One of the main features of colorectal cancer is that there are considerable differences between the tumors of individual patients - at genetic level and hence in terms of the response to treatment too. Researchers from the German Cancer Consortium (DKTK) have developed a method that allows these di more

An artificial intelligence platform developed at the Max Delbrück Center for Molecular Medicine (MDC) can analyze genomic data extremely quickly, picking out key patterns to classify different types of colorectal tumors and improve the drug discovery process. The deeper analysis shows some colorecta more

Evotec SE and Indivumed GmbH announced that the first milestone has been successfully achieved in their joint collaboration to identify new therapeutic targets for the treatment of colorectal cancer. Under the terms of the collaboration agreement, Evotec received full access to the colorectal cancer more

Colorectal cancer patients often relapse due to resistance to chemotherapy. The tumor microenvironment is known to contribute to tumor aggressiveness and chemoresistance, but the underlying mechanisms remain elusive. In the current study, we have shown that cancer-associated fibroblasts (CAFs) which more

by Michael B. Burns, Emmanuel Montassier, Juan Abrahante, Sambhawa Priya, David E. Niccum, Alexander Khoruts, Timothy K. Starr, Dan Knights, Ran Blekhman Variation in the gut microbiome has been linked to colorectal cancer (CRC), as well as to host genetic variation. However, we do not know wheth more

by Oriol Ros, Pablo José Barrecheguren, Tiziana Cotrufo, Martina Schaettin, Cristina Roselló-Busquets, Alba Vílchez-Acosta, Marc Hernaiz-Llorens, Ramón Martínez-Marmol, Fausto Ulloa, Esther T. Stoeckli, Sofia J. Araújo, Eduardo Soriano Axonal growth and guidance rely on correct growth cone respon more