Cell Therapies

Companies Cell Therapies

Poseida Therapeutics, Inc., USA

Poseida Therapeutics is translating best-in-class gene engineering technologies into lifesaving cell therapies. The company is developing CAR T-cell immunotherapies for multiple myeloma, prostate and other cancer types, as well as gene therapies for orphan diseases. more

Histide AG, Switzerland

Histide™ is a biotech intellectual property platform company pioneering a new class of non-mutagenic extracellular therapeutic agents called Cell Recoding Molecules™ (CRMs). This innovative platform builds on Histide’s expertise in the mechanisms underlying the cell’s microenvironmental sensing and more

BlueRock Therapeutics, USA

BlueRock Therapeutics is a leading engineered cell therapy company with a mission to develop regenerative medicines for intractable diseases. BlueRock Therapeutics’ CELL+GENE™ platform harnesses the power of cells for new medicines across neurology, cardiology and immunology indications. BlueRock Th more

News Cell Therapies

• Merck Becomes the First to Use Acoustic Technology for Cell Therapy Manufacturing

  Merck announced it has acquired FloDesign Sonics, of Wilbraham, Massachusetts, USA, developer of a unique acoustic cell processing platform for the industrialization of cell and gene therapy manufacturing. Financial details were not disclosed. “Chimeric antigen receptor T cell therapies, or CAR-T fo more

• Bayer acquires BlueRock Therapeutics

  Bayer AG and BlueRock Therapeutics announced an agreement under which Bayer will fully acquire BlueRock Therapeutics, a privately held US-headquartered biotechnology company focused on developing engineered cell therapies in the fields of neurology, cardiology and immunology, using a proprietary ind more

• Making systems robust: Artificial genetic regulatory network introduced into living cell for the first time
  

  Both nature and technology rely on integral feedback mechanisms to ensure that systems resist external perturbations. ETH researchers have now used synthetic biology to design a new mechanism of this sort from scratch. For the first time, they have introduced it into a living cell as an artificial g more

Publications Cell Therapies

• The global landscape of cancer cell therapy

  The global landscape of cancer cell therapy The global landscape of cancer cell therapy, Published online: 25 May 2018; doi:10.1038/nrd.2018.74 How many cancer cell therapies are being developed? To harmonize efforts in this arena, the Cancer Research Institute has curated a database that includes more

• Prevention and treatment of relapse after stem cell transplantation by cellular therapies

  Despite recent advances in reducing therapy-related mortality after allogeneic stem cell transplantation (alloSCT) relapse remains the major cause of treatment failure and little progress has been achieved in the last decades. At the 3rd International Workshop on Biology, Prevention, and Treatment o more

• Cell therapy trials for heart regeneration — lessons learned and future directions

  The effects of cell therapy on heart regeneration in patients with chronic cardiomyopathy have been assessed in several clinical trials. These trials can be categorized as those using noncardiac stem cells, including mesenchymal stem cells, and those using cardiac-committed cells, including KIT+ car more