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Stem Cells

Companies Stem Cells

Braingineering Technologies (BTech), Luxembourg

With a new high-tech 3D stem cell technology Braingineering Technologies (BTech), a designated spin-off of the Luxembourg Centre for Systems Biomedicine (LCSB), supports pharmaceutical companies in the drug discovery and preclinical testing phase to increase their efficiency and the success rate of more

Products Stem Cells

Spin Your Organs

Complex seamless scaffold for 3D-culturing of stem- and tissue cells under defined, reproducible conditions more

Stem cells like hypoxia

Providing regulated O2 atmosphere in combination with a sterile laminar flow function, the SCI-tive is a must-have for cell research more

News Stem Cells

  • Developing drugs to treat Parkinson’s disease

    Representatives of the University of Luxembourg and the technology company Ksilink which is developing novel patient-based forms of therapy, signed a collaboration agreement last Friday. The agreement constitutes the framework for collaboration between Ksilink and the Luxembourg Centre for Systems B more

  • Fluorescent molecules reveal how cancer cells are inhibited

    A team of researchers at Lund University in Sweden has developed a fluorescent variant of a molecule that inhibits cancer stem cells. Capturing images of when the molecule enters a cell has enabled the researchers, using cell-biological methods, to successfully describe how and where the molecule co more

  • With gene editing, researchers cure blood disorder in fetal mice

    With the combined efforts of three Yale laboratories, researchers conducted the first demonstration of site-specific gene editing in a fetus, correcting a mutation that causes a severe form of anemia. The technique, described in a paper published June 26 in Nature Communications, involves an intrave more

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Videos Stem Cells

Stem cells like hypoxia

Human cells exist in the body in a surrounding of 2-8 % oxygen. The ambient air, normally used in cell culture incubators and workbenches, however, has an oxygen content of about 21 %. When working with primary and stem cells or with cultured cancer cells, it is important to mimic physiological cond more

Spin Your Organs

"Produce replacement organs in your own laboratory." What still sounds like a dream of the future, is actually – partly – already possible due to recent progresses in technology. Based on biocompatible carrier materials, novel three-dimensional structures can be designed by means of a sophisticated more

New Lung “Organoids” In a Dish Mimic Features of Full-Size Lung

Researchers at Columbia University Medical Center have developed three-dimensional lung bud "organoids" from human pluripotent stem cells. The "mini organs" could be used to model lung diseases such as pulmonary fibrosis and respiratory syncytial virus infection.The research was carried out in t ... more

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White papers Stem Cells

  • HelpCorner - Transfection

    Transfection is the delivery of DNA, RNA, proteins, and macromelecules into eukaryotic cells. The goals for transfection include the study of gene function and regulation as well as protein expression and function. It is also used for gene silencing more

  • Twin Guard: Sample security in long term storage

    Secure sample storage plays a critical role in a wide range of medical and life science projects today where there is a need to maintain often very large numbers of biological samples at low and stable temperatures for long periods. Globally, close more

  • HelpCorner - xCELLigence System

    Automated monitoring and data collection contribute to significant time savings when using the xCELLigence System, with only a few minutes of extra setup time. For example, in a 96-well plate, 32 different conditions can be tested in triplicate; the more

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Events Stem Cells

Conference
29-07 – 03-08
2018
Newport, US

Neural Development

The 2018 Gordon Research Conference (GRC) on Neural Development in Newport, Rhode Island will bring together an international group of scientists that have made breakthroughs in our understanding of nervous system development. Sophisticated mechanisms synergize throughout development to create and d

Course
18-08 – 19-08
2018
Waterville Valley, US

Tissue Niches and Resident Stem Cells in Adult Epithelia (GRS)

The newly established Gordon Research Seminar on Tissue Niches and Resident Stem Cells in Adult Epithelia is designed to provide a venue for postdoctoral trainees and graduate students to openly present their research to their peers, to share and discuss unpublished data and technical breakthroughs

Conference
19-08 – 24-08
2018
West Dover, US

Mechanisms of Epilepsy and Neuronal Synchronization

The main goal of the study of epilepsy is to identify the causes and complex mechanisms that underlie the abnormal, synchronous, electrical discharges that occur in hyperexcitable neuronal networks during seizures. The specific theme of this GRC is “Translating mechanisms into therapies”, and will f

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Publications Stem Cells

  • Notch ligand Dll1 mediates cross-talk between mammary stem cells and the macrophageal niche

    The stem cell niche is a specialized environment that dictates stem cell function during development and homeostasis. We show that Dll1, a Notch pathway ligand, is enriched in mammary gland stem cells (MaSCs) and mediates critical interactions with stromal macrophages in the surrounding niche in mo more

  • Cross-talk in the mammary gland

    Stem Cells Macrophages engulf damaged and dead cells to clear infection, but they also participate in tissue regeneration. Chakrabarti et al. expand the macrophage repertoire for mammary gland development (see the Perspective by Kannan and Eaves). Mammary gland stem cells secrete the Notch ligand more

  • Macrophages stimulate mammary stem cells

    The adult mammary gland is a bilayered branching epithelial structure consisting of an outer layer of basal cells and an inner layer of luminal cells. The neonatal structure expands rapidly during puberty and then undergoes cyclic growth in response to the changing hormonal stimuli (progesterone and more

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Market studies Stem Cells

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